Literature DB >> 7714543

Ophirapstanol trisulfate, a new biologically active steroid sulfate from the deep water marine sponge Topsentia ophiraphidites.

S P Gunasekera1, S H Sennett, M Kelly-Borges, R W Bryant.   

Abstract

Ophirapstanol trisulfate [1], a new steroid trisulfate related to sokotrasterol trisulfate was isolated from a deep water marine sponge Topsentia ophiraphidites. Compound 1 exhibited significant inhibition in the guanosine diphosphate/G-protein RAS exchange assay. The structure elucidation of 1 and ophirapstanol [2] by nmr spectroscopy is described.

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Year:  1994        PMID： 7714543     DOI： 10.1021/np50114a024

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  6 in total

1.  Tulongicin, an Antibacterial Tri-Indole Alkaloid from a Deep-Water Topsentia sp. Sponge.

Authors:  Hong-Bing Liu; Gianluigi Lauro; Robert D O'Connor; Katheryn Lohith; Michelle Kelly; Patrick Colin; Giuseppe Bifulco; Carole A Bewley
Journal:  J Nat Prod       Date:  2017-08-24       Impact factor: 4.050

2.  Fibrosterol sulfates from the Philippine sponge Lissodendoryx (Acanthodoryx) fibrosa: sterol dimers that inhibit PKCzeta.

Authors:  Emily L Whitson; Tim S Bugni; Priya S Chockalingam; Gisela P Concepcion; Xidong Feng; Guixian Jin; Mary Kay Harper; Gina C Mangalindan; Leonard A McDonald; Chris M Ireland
Journal:  J Org Chem       Date:  2009-08-21       Impact factor: 4.354

3.  Sulfated steroid-amino acid conjugates from the Irish marine sponge Polymastia boletiformis.

Authors:  Vangelis Smyrniotopoulos; Margaret Rae; Sylvia Soldatou; Yuanqing Ding; Carsten W Wolff; Grace McCormack; Christina M Coleman; Daneel Ferreira; Deniz Tasdemir
Journal:  Mar Drugs       Date:  2015-03-24       Impact factor: 5.118

Review 4.  Steroids from sponges: recent reports.

Authors:  A Aiello; E Fattorusso; M Menna
Journal:  Steroids       Date:  1999-10       Impact factor: 2.668

Review 5.  Sulfated and Sulfur-Containing Steroids and Their Pharmacological Profile.

Authors:  Tatyana A Pounina; Tatyana A Gloriozova; Nick Savidov; Valery M Dembitsky
Journal:  Mar Drugs       Date:  2021-04-24       Impact factor: 5.118

6.  Spheciosterol sulfates, PKCzeta inhibitors from a philippine sponge Spheciospongia sp.

Authors:  Emily L Whitson; Tim S Bugni; Priya S Chockalingam; Gisela P Concepcion; Mary Kay Harper; Min He; John N A Hooper; Gina C Mangalindan; Frank Ritacco; Chris M Ireland
Journal:  J Nat Prod       Date:  2008-06-18       Impact factor: 4.050
  6 in total

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