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Literature DB >> 7701468

Hepatotoxicity caused by the combined action of isoniazid and rifampicin.

Abstract

A 35 year old black Somalian woman with miliary tuberculosis developed hepatotoxicity after a few days of treatment with isoniazid, rifampicin, pyrazinamide, and ethambutol. After withdrawal of all drugs the liver profile returned to normal and remained so after challenge with isoniazid. Hepatotoxicity recurred when rifampicin was added, but it was well tolerated when reintroduced without isoniazid.

Entities: Chemical Disease Species

Mesh：

Substances：
Isoniazid
Rifampin

Year: 1995 PMID： 7701468 PMCID： PMC473930 DOI： 10.1136/thx.50.2.213

Source DB: PubMed Journal: Thorax ISSN： 0040-6376 Impact factor: 9.139

5 in total

Review 1. Drug-induced liver disease.

Authors: J H Lewis; H J Zimmerman
Journal: Med Clin North Am Date: 1989-07 Impact factor: 5.456

2. Toxic hepatitis with isoniazid and rifampin. A meta-analysis.

Authors: M A Steele; R F Burk; R M DesPrez
Journal: Chest Date: 1991-02 Impact factor: 9.410

3. Toxicity form rifampicin plus isoniazid and rifampicin plus ethambutol therapy.

Authors: A W Lees; G W Allan; J Smith; W F Tyrrell; R J Fallon
Journal: Tubercle Date: 1971-09

4. Isoniazid-related hepatitis: a U.S. Public Health Service cooperative surveillance study.

Authors: D E Kopanoff; D E Snider; G J Caras
Journal: Am Rev Respir Dis Date: 1978-06

5. Rifampin-induced release of hydrazine from isoniazid. A possible cause of hepatitis during treatment of tuberculosis with regimens containing isoniazid and rifampin.

Authors: G R Sarma; C Immanuel; S Kailasam; A S Narayana; P Venkatesan
Journal: Am Rev Respir Dis Date: 1986-06

5 in total

12 in total

1. Hepatotoxicity of antituberculosis drugs.

Authors: L P Ormerod; C Skinner; J Wales
Journal: Thorax Date: 1996-02 Impact factor: 9.139

2. Diallyl trisulfide protects the liver against hepatotoxicity induced by isoniazid and rifampin in mice by reducing oxidative stress and activating Kupffer cells.

Authors: Yilin Yang; Lulu Jiang; Shuo Wang; Tao Zeng; Keqin Xie
Journal: Toxicol Res (Camb) Date: 2016-04-01 Impact factor: 3.524

3. Toxicity of isoniazid and rifampicin combination.

Authors: I A Campbell
Journal: Thorax Date: 1995-07 Impact factor: 9.139

Review 4. Oxidative Stress and First-Line Antituberculosis Drug-Induced Hepatotoxicity.

Authors: Wing Wai Yew; Kwok Chiu Chang; Denise P Chan
Journal: Antimicrob Agents Chemother Date: 2018-07-27 Impact factor: 5.191

5. Rifampicin-isoniazid induced fatal fulminant hepatitis during treatment of latent tuberculosis: A case report and literature review.

Authors: Fahmi Yousef Khan; Fatima Rasoul
Journal: Indian J Crit Care Med Date: 2010-04

6. Antituberculosis drug-induced hepatotoxicity in children.

Authors: Peter R Donald
Journal: Pediatr Rep Date: 2011-06-16

Review 7. Hepatic safety of antibiotics used in primary care.

Authors: Raúl J Andrade; Paul M Tulkens
Journal: J Antimicrob Chemother Date: 2011-05-17 Impact factor: 5.790

8. Protective effects of salep against isoniazid liver toxicity in wistar rats.

Authors: Hossein Kargar Jahromi; Morteza Pourahmad; Hassan Ali Abedi; Mohadeseh Karimi; Zahra Kargar Jahromi
Journal: J Tradit Complement Med Date: 2017-06-21

Review 9. Something Old, Something New: Ion Channel Blockers as Potential Anti-Tuberculosis Agents.

Authors: Steven C Mitini-Nkhoma; Elizabeth T Chimbayo; David T Mzinza; David V Mhango; Aaron P Chirambo; Christine Mandalasi; Agness E Lakudzala; Dumizulu L Tembo; Kondwani C Jambo; Henry C Mwandumba
Journal: Front Immunol Date: 2021-06-24 Impact factor: 7.561

Review 10. Ayurvedic management of pulmonary tuberculosis: A systematic review.

Authors: Janmejaya Samal
Journal: J Intercult Ethnopharmacol Date: 2015-11-13