Literature DB >> 7698310

Phase separation in cytoplasm, due to macromolecular crowding, is the basis for microcompartmentation.

H Walter1, D E Brooks.   

Abstract

The macromolecular diversity and concentrations in the fluid phase of cytoplasm constitute conditions necessary and sufficient for aqueous phase separation. Consequences of phase separation in cytoplasm, including its 'compartmentation', are inferred from analogies with the physicochemical properties of aqueous two-phase systems and with the partitioning behavior of biomaterials in them.

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Year:  1995        PMID: 7698310     DOI: 10.1016/0014-5793(95)00159-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  51 in total

Review 1.  Osmosensing by bacteria: signals and membrane-based sensors.

Authors:  J M Wood
Journal:  Microbiol Mol Biol Rev       Date:  1999-03       Impact factor: 11.056

2.  Protein self-association induced by macromolecular crowding: a quantitative analysis by magnetic relaxation dispersion.

Authors:  Karim Snoussi; Bertil Halle
Journal:  Biophys J       Date:  2005-01-21       Impact factor: 4.033

3.  Dynamic microcompartmentation in synthetic cells.

Authors:  M Scott Long; Clinton D Jones; Marcus R Helfrich; Lauren K Mangeney-Slavin; Christine D Keating
Journal:  Proc Natl Acad Sci U S A       Date:  2005-03-23       Impact factor: 11.205

4.  Radial compression of microtubules and the mechanism of action of taxol and associated proteins.

Authors:  Daniel J Needleman; Miguel A Ojeda-Lopez; Uri Raviv; Kai Ewert; Herbert P Miller; Leslie Wilson; Cyrus R Safinya
Journal:  Biophys J       Date:  2005-08-12       Impact factor: 4.033

5.  On the origins of a crowded cytoplasm.

Authors:  Luis Acerenza; Martin Graña
Journal:  J Mol Evol       Date:  2006-09-26       Impact factor: 2.395

6.  Phase behavior of an intact monoclonal antibody.

Authors:  Tangir Ahamed; Beatriz N A Esteban; Marcel Ottens; Gijs W K van Dedem; Luuk A M van der Wielen; Marc A T Bisschops; Albert Lee; Christine Pham; Jörg Thömmes
Journal:  Biophys J       Date:  2007-04-20       Impact factor: 4.033

7.  Coarse-grained molecular simulation of diffusion and reaction kinetics in a crowded virtual cytoplasm.

Authors:  Douglas Ridgway; Gordon Broderick; Ana Lopez-Campistrous; Melania Ru'aini; Philip Winter; Matthew Hamilton; Pierre Boulanger; Andriy Kovalenko; Michael J Ellison
Journal:  Biophys J       Date:  2008-01-30       Impact factor: 4.033

8.  Macromolecular crowding induced elongation and compaction of single DNA molecules confined in a nanochannel.

Authors:  Ce Zhang; Pei Ge Shao; Jeroen A van Kan; Johan R C van der Maarel
Journal:  Proc Natl Acad Sci U S A       Date:  2009-09-16       Impact factor: 11.205

Review 9.  From water and ions to crowded biomacromolecules: in vivo structuring of a prokaryotic cell.

Authors:  Jan Spitzer
Journal:  Microbiol Mol Biol Rev       Date:  2011-09       Impact factor: 11.056

Review 10.  Macromolecular Crowding In Vitro, In Vivo, and In Between.

Authors:  Germán Rivas; Allen P Minton
Journal:  Trends Biochem Sci       Date:  2016-09-23       Impact factor: 13.807

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