Literature DB >> 769789

High mutagenicity and toxicity of a diol epoxide derived from benzo(a)pyrene.

P G Wislocki, A W Wood, R L Chang, W Levin, H Yagi, O Hernandez, D M Jerina, A H Conney.   

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Year:  1976        PMID: 769789     DOI: 10.1016/0006-291x(76)91246-8

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


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  19 in total

1.  Excision repair of benzo[a]pyrene-deoxyguanosine adducts in baby hamster kidney 21/C13 cells and in secondary mouse embryo fibroblasts C57BL/6J.

Authors:  K Shinohara; P A Cerutti
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

2.  Evolution of activation-detoxification enzyme patterns during precarcinogenesis in synergism: 3-methylcholanthrene and dimethylnitrosamine.

Authors:  D Y Lai; G M Bryant; S C Myers; Y T Woo; M F Argus; J C Arcos
Journal:  J Cancer Res Clin Oncol       Date:  1982       Impact factor: 4.553

3.  Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.

Authors:  M K Buening; P G Wislocki; W Levin; H Yagi; D R Thakker; H Akagi; M Koreeda; D M Jerina; A H Conney
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

4.  Effect of benzo[a]pyrene-diolepoxide on infectivity and in vitro translation of phage MS2 RNA.

Authors:  D Sagher; R G Harvey; W T Hsu; S B Weiss
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

5.  Metabolic activations of polycyclic hydrocarbons. Structure-activity relationships.

Authors:  R E Lehr; D M Jerina
Journal:  Arch Toxicol       Date:  1977-12-30       Impact factor: 5.153

Review 6.  Significance of various enzymes in the control of reactive metabolites.

Authors:  F Oesch
Journal:  Arch Toxicol       Date:  1987       Impact factor: 5.153

7.  Effect of histone acetylation on the formation and removal of B(a)P chromatin adducts.

Authors:  A Kootstra
Journal:  Nucleic Acids Res       Date:  1982-05-11       Impact factor: 16.971

8.  Mechanism of phage phiX174 DNA inactivation by benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide.

Authors:  W T Hsu; E J Lin; R G Harvey; S B Weiss
Journal:  Proc Natl Acad Sci U S A       Date:  1977-08       Impact factor: 11.205

9.  Mutagenicity and cytotoxicity of benz[alpha]anthracene diol epoxides and tetrahydro-epoxides: exceptional activity of the bay region 1,2-epoxides.

Authors:  A W Wood; R L Chang; W Levin; R E Lehr; M Schaefer-Ridder; J M Karle; D M Jerina; A H Conney
Journal:  Proc Natl Acad Sci U S A       Date:  1977-07       Impact factor: 11.205

Review 10.  Epoxides--is there a human health problem?

Authors:  M M Manson
Journal:  Br J Ind Med       Date:  1980-11
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