Literature DB >> 7696700

Positive-ion fast-atom bombardment tandem mass spectrometry of peptide nucleic acids.

T Takao1, H Fukuda, J Coull, Y Shimonishi.   

Abstract

The base sequence of synthetic peptide nucleic acids (PNAs), novel antisense agents, was analyzed by positive-ion fast-atom bombardment tandem mass spectrometry (FAB-MS/MS). Upon high-energy collisional activation decomposition, PNA oligomers provided apparent MS/MS product ions resulting from specific cleavage along the PNA backbone.

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Year:  1994        PMID: 7696700     DOI: 10.1002/rcm.1290081203

Source DB:  PubMed          Journal:  Rapid Commun Mass Spectrom        ISSN: 0951-4198            Impact factor:   2.419


  2 in total

1.  An experimental and theoretical study of the gas-phase decomposition of monoprotonated peptide nucleic acids.

Authors:  J W Flora; D D Shillady; D C Muddiman
Journal:  J Am Soc Mass Spectrom       Date:  2000-07       Impact factor: 3.109

2.  Complete sequencing of mono-deprotonated peptide nucleic acids by sustained off-resonance irradiation collision-induced dissociation.

Authors:  J W Flora; D C Muddiman
Journal:  J Am Soc Mass Spectrom       Date:  2001-07       Impact factor: 3.262

  2 in total

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