Literature DB >> 7693964

Hepatitis C virus infection: its role in chronic liver diseases.

Y Y Zhang1, L S Guo, Y D Zhang, L Li, D X Yu, F H Li, Y K Wang, Z Q Yu, L J Hao, B G Hansson.   

Abstract

In order to find out the infectious rate of hepatitis C virus (HCV) among chronic liver diseases, we investigated antibodies against hepatitis C virus and HCVRNA by method of ELISA, RIBA and RT-PCR in 410 patients with chronic liver disease. The prevalence of HCV infection was found to be 4%. Whereas the positive rate of HBsAg and HBV-DNA of these cases was 69% and 58%, respectively. There is no statistical significance between HCV infectious rate of patients with positive and negative HBsAg. The relative low infectious rate of HCV infection among chronic hepatic diseases indicates that HBV infection plays a more important role in causing chronic hepatitis than that of HCV. Thus, special emphasis should be paid to the preventive and therapeutic measures against hepatitis B in China.

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Year:  1993        PMID： 7693964     DOI： 10.1007/bf02887927

Source DB:  PubMed          Journal:  J Tongji Med Univ        ISSN： 0257-716X


  14 in total

1.  Non-specificity of anti-HCV test for seroepidemiological analysis.

Authors:  D C Wong; A R Diwan; L Rosen; J L Gerin; R G Johnson; A Polito; R H Purcell
Journal:  Lancet       Date:  1990-09-22       Impact factor: 79.321

2.  Detection of antibody against antigen expressed by molecularly cloned hepatitis C virus cDNA: application to diagnosis and blood screening for posttransfusion hepatitis.

Authors:  T Miyamura; I Saito; T Katayama; S Kikuchi; A Tateda; M Houghton; Q L Choo; G Kuo
Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

3.  Hepatitis C virus RNA in blood donor sera detected by the polymerase chain reaction: comparison with supplementary hepatitis C antibody assays.

Authors:  A Widell; A S Månsson; G Sundström; B G Hansson; E Nordenfelt
Journal:  J Med Virol       Date:  1991-12       Impact factor: 2.327

4.  Infection with delta agent in Sweden: introduction of a new hepatitis agent.

Authors:  B G Hansson; T Moestrup; A Widell; E Nordenfelt
Journal:  J Infect Dis       Date:  1982-10       Impact factor: 5.226

5.  Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis.

Authors:  H J Alter; R H Purcell; J W Shih; J C Melpolder; M Houghton; Q L Choo; G Kuo
Journal:  N Engl J Med       Date:  1989-11-30       Impact factor: 91.245

6.  Hepatitis C virus infection in an area hyperendemic for hepatitis B and chronic liver disease: the Taiwan experience.

Authors:  D S Chen; G C Kuo; J L Sung; M Y Lai; J C Sheu; P J Chen; P M Yang; H M Hsu; M H Chang; C J Chen
Journal:  J Infect Dis       Date:  1990-10       Impact factor: 5.226

7.  Anti-hepatitis C antibodies and non-A, non-B post-transfusion hepatitis in The Netherlands.

Authors:  C L van der Poel; H W Reesink; P N Lelie; A Leentvaar-Kuypers; Q L Choo; G Kuo; M Houghton
Journal:  Lancet       Date:  1989-08-05       Impact factor: 79.321

8.  Clinical and serological analysis of transfusion-associated hepatitis.

Authors:  H J Alter; P V Holland; A G Morrow; R H Purcell; S M Feinstone; Y Moritsugu
Journal:  Lancet       Date:  1975-11-01       Impact factor: 79.321

9.  An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis.

Authors:  G Kuo; Q L Choo; H J Alter; G L Gitnick; A G Redeker; R H Purcell; T Miyamura; J L Dienstag; M J Alter; C E Stevens
Journal:  Science       Date:  1989-04-21       Impact factor: 47.728

10.  Hepatitis C virus antibodies in chronic active hepatitis: pathogenetic factor or false-positive result?

Authors:  I G McFarlane; H M Smith; P J Johnson; G P Bray; D Vergani; R Williams
Journal:  Lancet       Date:  1990-03-31       Impact factor: 79.321
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