Literature DB >> 7689524

The role of the O-antigen lipopolysaccharide and capsule on an experimental Klebsiella pneumoniae infection of the rat urinary tract.

S Camprubí1, S Merino, V J Benedí, J M Tomás.   

Abstract

We obtained, by different methods, isogenic lipopolysaccharide (O antigen) and capsular polysaccharide (K antigen) mutants from Klebsiella pneumoniae strains able to induce experimental infections (cystitis and pyelonephritis) in rats. We compared the induction of experimental infections in rats by wild-type strains and the lipopolysaccharide and capsular polysaccharide mutants. The high-molecular mass lipopolysaccharide of K. pneumoniae is clearly implicated in the infection process of the rat urinary tract, whilst the capsular polysaccharide seems not to be involved to the same extent.

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Year:  1993        PMID： 7689524     DOI： 10.1016/0378-1097(93)90175-2

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN： 0378-1097            Impact factor:   2.742


  14 in total

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Review 2.  Natural pathogens of laboratory mice, rats, and rabbits and their effects on research.

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3.  Modeling Klebsiella pneumoniae pathogenesis by infection of the wax moth Galleria mellonella.

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4.  Comparison of the host responses to wild-type and cpsB mutant Klebsiella pneumoniae infections.

Authors:  Matthew S Lawlor; Scott A Handley; Virginia L Miller
Journal:  Infect Immun       Date:  2006-09       Impact factor: 3.441

5.  Cloning and sequencing of the Klebsiella pneumoniae O5 wb gene cluster and its role in pathogenesis.

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6.  A gene, uge, is essential for Klebsiella pneumoniae virulence.

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Journal:  Infect Immun       Date:  2004-01       Impact factor: 3.441

7.  Contribution of capsular and lipopolysaccharide antigens to the pathogenesis of Klebsiella pneumoniae respiratory tract infection.

Authors:  S Chhibber; S Aggarwal; V Yadav
Journal:  Folia Microbiol (Praha)       Date:  2003       Impact factor: 2.099

8.  The Klebsiella pneumoniae wabG gene: role in biosynthesis of the core lipopolysaccharide and virulence.

Authors:  Luis Izquierdo; Núria Coderch; Nuria Piqué; Emiliano Bedini; Maria Michela Corsaro; Susana Merino; Sandra Fresno; Juan M Tomás; Miguel Regué
Journal:  J Bacteriol       Date:  2003-12       Impact factor: 3.490

9.  Enhanced biofilm formation by Escherichia coli LPS mutants defective in Hep biosynthesis.

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Journal:  PLoS One       Date:  2012-12-28       Impact factor: 3.240

10.  Role of bacterial surface structures on the interaction of Klebsiella pneumoniae with phagocytes.

Authors:  Catalina March; Victoria Cano; David Moranta; Enrique Llobet; Camino Pérez-Gutiérrez; Juan M Tomás; Teresa Suárez; Junkal Garmendia; José A Bengoechea
Journal:  PLoS One       Date:  2013-02-15       Impact factor: 3.240
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