| Literature DB >> 7687323 |
J D Tucker1, A Auletta, M C Cimino, K L Dearfield, D Jacobson-Kram, R R Tice, A V Carrano.
Abstract
This paper reviews the ability of a number of chemicals to induce sister-chromatid exchanges (SCEs). The SCE data for animal cells in vivo and in vitro, and human cells in vitro are presented in 6 tables according to their relative effectiveness. A seventh table summarizes what is known about the effects of specific chemicals on SCEs for humans exposed in vivo. The data support the concept that SCEs provide a useful indication of exposure, although the mechanism and biological significance of SCE formation still remain to be elucidated.Entities:
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Year: 1993 PMID: 7687323 DOI: 10.1016/0165-1110(93)90001-4
Source DB: PubMed Journal: Mutat Res ISSN: 0027-5107 Impact factor: 2.433