Literature DB >> 768630

[Present state in synchronization therapy of malignant tumors and acute leukemias (author's transl)].

H Sauer, W Wilmanns.   

Abstract

Chemotherapy of malignant tumors can be made more effective by synchronization of the cell cycle. Synchronization therapy consists of a synchronizing step (phase I), an interval and a cytocidal step (phase II). Some regimens till now approved in clinical treatment are presented. The results are found to be encouraging. In all schedules three effects work together namely synchronization recruitment, summation.

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Year:  1976        PMID： 768630     DOI： 10.1007/bf01469125

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN： 0023-2173


  17 in total

1.  [Experimental and theoretical studies on the in-vivo production of a partially synchronous proliferating cell population with vincristine].

Authors:  R Maidhof; W Jellinghaus; B Schultze; W Maurer
Journal:  Dtsch Med Wochenschr       Date:  1975-01-10       Impact factor: 0.628

2.  Differential lethal effect of cytotoxic agents on proliferating and nonproliferating lymphoid cells.

Authors:  H Lin
Journal:  Cancer Res       Date:  1973-07       Impact factor: 12.701

3.  Correlation of cytosine arabinoside-induced increment in growth fraction of leukemic blast cells with clinical response.

Authors:  W R Vogler; L E Cooper; D P Groth
Journal:  Cancer       Date:  1974-03       Impact factor: 6.860

4.  Cytarabine for acute leukemia in adults. Effect of schedule on therapeutic response.

Authors:  J N Bickers; E A Gehan; E J Freireich; C A Coltman; H E Wilson; J S Hewlett; W J Stuckey; E J Van Slyck
Journal:  Arch Intern Med       Date:  1974-02

5.  Accumulation of S-phase cells in the bone marrow of patients with acute leukemia by cytosine arabinoside.

Authors:  T Büchner; B Barlogie; U Asseburg; W Hiddemann; D Kamanabroo; W Göhde
Journal:  Blut       Date:  1974-04

6.  Survival responses of dividing and nondividing mammalian cells after treatment with hydroxyurea, arabinosylcytosine, or adriamycin.

Authors:  S C Barranco; J K Novak
Journal:  Cancer Res       Date:  1974-07       Impact factor: 12.701

7.  [Cytostatic treatment with a combination of vincristine and ifosfamide].

Authors:  G Hartwich; W Tschätsch; H Lutz
Journal:  Dtsch Med Wochenschr       Date:  1973-06-15       Impact factor: 0.628

8.  [A new method for the treatment of advanced neoplasms].

Authors:  U Ganzer; H R Nitze; G Rosemann
Journal:  Med Welt       Date:  1972-02-26

9.  [First clinical results of radiotherapy following partial synchronization by bleomycin].

Authors:  M Wannenmacher; E Esser; J Schumann
Journal:  Strahlentherapie       Date:  1975-02

10.  [Pharmakokinetics of hydroxy-urea. Therapy of acute myeoblastic leukemias using synchronization and recruitment effects (author' transl)].

Authors:  H Sauer; R Pelka; W Wilmanns
Journal:  Klin Wochenschr       Date:  1976-03-01
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  3 in total

1.  [Partial synchronization of tumor cells in vivo with hydroxyurea (author's transl)].

Authors:  R Hartenstein; K Pfundmair; K Possinger
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1977

2.  Therapy of solid Walker carcinosarcoma 256 with bleomycin after synchronization with hydroxyurea.

Authors:  M Volm; J Mattern; N Weber; K Wayss
Journal:  Cancer Chemother Pharmacol       Date:  1980       Impact factor: 3.333

3.  [Pharmakokinetics of hydroxy-urea. Therapy of acute myeoblastic leukemias using synchronization and recruitment effects (author' transl)].

Authors:  H Sauer; R Pelka; W Wilmanns
Journal:  Klin Wochenschr       Date:  1976-03-01
  3 in total

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