Literature DB >> 7684825

Sequence-specific scission of DNA by RNAs linked to a chemical nuclease.

D S Sigman1, C H Chen, M B Gorin.   

Abstract

RNAs linked to the chemical nuclease 1,10-phenanthroline-copper cut double-stranded DNA of complementary sequence. This cleavage reaction is applicable to all sequences and can be used to measure the distance between marker genes in base pairs, map the size of a transcription unit and define positions of chromosomal breakpoints.

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Year:  1993        PMID： 7684825     DOI： 10.1038/363474a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  6 in total

1.  Using molecular beacons as a sensitive fluorescence assay for enzymatic cleavage of single-stranded DNA.

Authors:  J J Li; R Geyer; W Tan
Journal:  Nucleic Acids Res       Date:  2000-06-01       Impact factor: 16.971

2.  Kinetics of spontaneous displacement of RNA from heteroduplexes by DNA.

Authors:  R Landgraf; K S Ramamurthi; D S Sigman
Journal:  Nucleic Acids Res       Date:  1996-08-15       Impact factor: 16.971

3.  Double stranded scission of DNA directed through sequence-specific R-loop formation.

Authors:  R Landgraf; C H Chen; D S Sigman
Journal:  Nucleic Acids Res       Date:  1995-09-11       Impact factor: 16.971

4.  R-loop stability as a function of RNA structure and size.

Authors:  R Landgraf; C H Chen; D S Sigman
Journal:  Nucleic Acids Res       Date:  1995-09-11       Impact factor: 16.971

5.  Modified RNA sequence pools for in vitro selection.

Authors:  Y Lin; Q Qiu; S C Gill; S D Jayasena
Journal:  Nucleic Acids Res       Date:  1994-12-11       Impact factor: 16.971

6.  Generation of artificial sequence-specific nucleases via a preassembled inert-template.

Authors:  Xianjin Xiao; Tongbo Wu; Feidan Gu; Meiping Zhao
Journal:  Chem Sci       Date:  2015-12-07       Impact factor: 9.825
  6 in total

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