| Literature DB >> 7682538 |
L Leoncini1, C Vindigni, T Megha, I Funtò, L Pacenti, M Musarò, A Renieri, M Seri, J Anagnostopoulos, P Tosi.
Abstract
Sixty-five unselected cases of gastric cancer have been analysed for EBV DNA by polymerase chain reaction, in situ hybridization and immunohistochemistry for CD21 antigen expression. Four cases were found EBV-positive by PCR, while ISH yielded positive results in 3 of these cases, demonstrating EBV in the nuclei of cancerous cells. CD21 antigen was expressed in cancerous cells in all 3 ISH-positive cases. All the EBV-positive cancers of the present series were poorly to moderately differentiated adenocarcinomas with prominent lymphoid infiltration. These results are discussed also on the basis of the literature.Entities:
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Year: 1993 PMID： 7682538 DOI： 10.1002/ijc.2910530605
Source DB: PubMed Journal: Int J Cancer ISSN： 0020-7136 Impact factor: 7.396