Literature DB >> 7680119

Determinants of Escherichia coli RNase P cleavage site selection: a detailed in vitro and in vivo analysis.

S G Svärd1, L A Kirsebom.   

Abstract

The location of the Escherichia coli RNase P cleavage site was studied both in vitro and in vivo. We show that selection of the cleavage site is dependent on the nucleotide at the cleavage site and the length of the acceptor-stem. Within the acceptor-stem the number of nucleotides on the 5'-half of the acceptor-stem appears to be the important determinant, rather than the number of base pairs in the acceptor-stem. We also demonstrate that the length of the T-stem and a G to C substitution at position 57 in the tRNA(Tyr)Su3 precursor influence the location of the cleavage site under certain conditions. With respect to the function of the subunits of RNase P our data suggest that the nucleotide at position 333 in M1 RNA, and the C5 protein, are important for the identification of the cleavage site.

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Year:  1993        PMID： 7680119      PMCID： PMC309135          DOI： 10.1093/nar/21.3.427

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  28 in total

1.  Ribonuclease P RNA and protein subunits from bacteria.

Authors:  J W Brown; N R Pace
Journal:  Nucleic Acids Res       Date:  1992-04-11       Impact factor: 16.971

2.  The kinetics and specificity of cleavage by RNase P is mainly dependent on the structure of the amino acid acceptor stem.

Authors:  L A Kirsebom; S G Svärd
Journal:  Nucleic Acids Res       Date:  1992-02-11       Impact factor: 16.971

3.  Important 2'-hydroxyl groups in model substrates for M1 RNA, the catalytic RNA subunit of RNase P from Escherichia coli.

Authors:  J P Perreault; S Altman
Journal:  J Mol Biol       Date:  1992-07-20       Impact factor: 5.469

4.  A single mutation in loop IV of Escherichia coli SuIII tRNA blocks processing at both 5'- and 3'-ends of the precursor tRNA.

Authors:  R M Reilly; U L RajBhandary
Journal:  J Biol Chem       Date:  1986-02-25       Impact factor: 5.157

5.  Correlation of nonsense sites in the lacI gene with specific codons in the nucleotide sequence.

Authors:  J H Miller; C Coulondre; P J Farabaugh
Journal:  Nature       Date:  1978-08-24       Impact factor: 49.962

6.  The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme.

Authors:  C Guerrier-Takada; K Gardiner; T Marsh; N Pace; S Altman
Journal:  Cell       Date:  1983-12       Impact factor: 41.582

7.  Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates.

Authors:  J F Milligan; D R Groebe; G W Witherell; O C Uhlenbeck
Journal:  Nucleic Acids Res       Date:  1987-11-11       Impact factor: 16.971

8.  Several regions of a tRNA precursor determine the Escherichia coli RNase P cleavage site.

Authors:  S G Svärd; L A Kirsebom
Journal:  J Mol Biol       Date:  1992-10-20       Impact factor: 5.469

9.  Nucleotide sequence of the gene encoding the RNA subunit (M1 RNA) of ribonuclease P from Escherichia coli.

Authors:  R E Reed; M F Baer; C Guerrier-Takada; H Donis-Keller; S Altman
Journal:  Cell       Date:  1982-09       Impact factor: 41.582

10.  Three-dimensional structure of yeast phenylalanine transfer RNA: folding of the polynucleotide chain.

Authors:  S H Kim; G J Quigley; F L Suddath; A McPherson; D Sneden; J J Kim; J Weinzierl; A Rich
Journal:  Science       Date:  1973-01-19       Impact factor: 47.728
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  15 in total

1.  Substrate binding and catalysis by ribonuclease P from cyanobacteria and Escherichia coli are affected differently by the 3' terminal CCA in tRNA precursors.

Authors:  A Pascual; A Vioque
Journal:  Proc Natl Acad Sci U S A       Date:  1999-06-08       Impact factor: 11.205

2.  Mutations which alter the elbow region of tRNA2Gly reduce T4 gene 60 translational bypassing efficiency.

Authors:  A J Herr; J F Atkins; R F Gesteland
Journal:  EMBO J       Date:  1999-05-17       Impact factor: 11.598

3.  Different cleavage sites are aligned differently in the active site of M1 RNA, the catalytic subunit of Escherichia coli RNase P.

Authors:  J Kufel; L A Kirsebom
Journal:  Proc Natl Acad Sci U S A       Date:  1996-06-11       Impact factor: 11.205

Review 4.  External guide sequence technology: a path to development of novel antimicrobial therapeutics.

Authors:  Carol Davies-Sala; Alfonso Soler-Bistué; Robert A Bonomo; Angeles Zorreguieta; Marcelo E Tolmasky
Journal:  Ann N Y Acad Sci       Date:  2015-04-09       Impact factor: 5.691

5.  Precursor of C4 antisense RNA of bacteriophages P1 and P7 is a substrate for RNase P of Escherichia coli.

Authors:  R K Hartmann; J Heinrich; J Schlegl; H Schuster
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-20       Impact factor: 11.205

6.  Expression, purification and characterization of the recombinant ribonuclease P protein component from Bacillus subtilis.

Authors:  S Niranjanakumari; J C Kurz; C A Fierke
Journal:  Nucleic Acids Res       Date:  1998-07-01       Impact factor: 16.971

7.  Cross talk between the +73/294 interaction and the cleavage site in RNase P RNA mediated cleavage.

Authors:  Mathias Brännvall; Ema Kikovska; Leif A Kirsebom
Journal:  Nucleic Acids Res       Date:  2004-10-11       Impact factor: 16.971

8.  tRNA requirements for glyQS antitermination: a new twist on tRNA.

Authors:  Mary R Yousef; Frank J Grundy; Tina M Henkin
Journal:  RNA       Date:  2003-09       Impact factor: 4.942

9.  Binding of C5 protein to P RNA enhances the rate constant for catalysis for P RNA processing of pre-tRNAs lacking a consensus (+ 1)/C(+ 72) pair.

Authors:  Lei Sun; Frank E Campbell; Lindsay E Yandek; Michael E Harris
Journal:  J Mol Biol       Date:  2009-11-13       Impact factor: 5.469

10.  Base pairing between Escherichia coli RNase P RNA and its substrate.

Authors:  L A Kirsebom; S G Svärd
Journal:  EMBO J       Date:  1994-10-17       Impact factor: 11.598
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