Literature DB >> 7678120

Nitric oxide synthase activities in human myocardium.

A J de Belder1, M W Radomski, H J Why, P J Richardson, C A Bucknall, E Salas, J F Martin, S Moncada.   

Abstract

Myocardial constitutive and inducible nitric oxide (NO) synthase activities were measured in right ventricular tissue from 17 patients with dilated cardiomyopathy (DCM). A significant activity of inducible enzyme was accompanied by a low activity of the constitutive NO synthase. Thus, the myocardium has the capacity to express both NO synthases. NO may have a physiological as well as a pathological role in the human myocardium.

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Year:  1993        PMID: 7678120     DOI: 10.1016/0140-6736(93)92559-c

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  41 in total

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