Literature DB >> 767318

Discontinuous synthesis of lac messenger ribonucleic acid in a mutant of Escherichia coli with a new lac promoter.

J Bruenn, W Kane.   

Abstract

A mutant of Escherichia coli with a new promoter for the lac operon exhibits dramatic discontinuities in the synthesis of lac messenger ribonucleic acid after induction. These discontinuities immediately precede similar discontinuities in the synthesis of beta-galactosidase. The discontinuous synthesis of beta-galactosidase persists after addition of rifampin.

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Year:  1976        PMID: 767318      PMCID: PMC236178          DOI: 10.1128/jb.125.3.1013-1017.1976

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  8 in total

1.  Existence and possible roles of transcriptional barriers in T7 DNA early region as shown by electron microscopy.

Authors:  J L Darlix; M Horaist
Journal:  Nature       Date:  1975-07-24       Impact factor: 49.962

2.  KINETICS OF INDUCED ENZYME SYNTHESIS. DETERMINATION OF THE MEAN LIFE OF GALACTOSIDASE-SPECIFIC MESSENGER RNA.

Authors:  A KEPES
Journal:  Biochim Biophys Acta       Date:  1963-10-15

3.  Genetic mapping of a new promoter for the lac operon.

Authors:  J Bruenn; P Le Lucia-Curtin
Journal:  J Mol Biol       Date:  1975-04-05       Impact factor: 5.469

4.  Inhibition of lacZ gene translation initiation in trp-lac fusion strains.

Authors:  W S Reznikoff; C A Michels; T G Cooper; A E Silverstone; B Magasanik
Journal:  J Bacteriol       Date:  1974-03       Impact factor: 3.490

5.  Evidence for two sites in the lac promoter region.

Authors:  J Beckwith; T Grodzicker; R Arditti
Journal:  J Mol Biol       Date:  1972-08-14       Impact factor: 5.469

6.  Role of cyclic adenosine 3',5'-monophosphate and the cyclic adenosine 3',5'-monophosphate receptor protein in the initiation of lac transcription.

Authors:  E De Crombrugghe; B Chen; W B Anderson; M E Gottesman; R L Perlman; I Pastan
Journal:  J Biol Chem       Date:  1971-12-10       Impact factor: 5.157

7.  The nucleotide sequence of the lactose messenger ribonucleic acid transcribed from the UV5 promoter mutant of Escherichia coli.

Authors:  N M Maizels
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205

8.  A mutant of Escherichia coli with a new, highly efficient promoter for the lactose operon.

Authors:  J Bruenn; H Hollingsworth
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205

  8 in total

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