Literature DB >> 4590169

A mutant of Escherichia coli with a new, highly efficient promoter for the lactose operon.

J Bruenn, H Hollingsworth.   

Abstract

We have isolated a mutant of E. coli whose maximal rate of synthesis of lac mRNA is 25-fold greater than that of its parental wild-type strain. The mutant also shows alterations in the kinetics of beta-galactosidase synthesis, the functional half-life of beta-galactosidase mRNA, and the properties of lac repressor.

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Year:  1973        PMID： 4590169      PMCID： PMC427308          DOI： 10.1073/pnas.70.12.3693

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  18 in total

1.  Location of the genes for 16S and 23S ribosomal RNA in the genetic map of Escherichia coli.

Authors:  M T Yu; C W Vermeulen; K C Atwood
Journal:  Proc Natl Acad Sci U S A       Date:  1970-09       Impact factor: 11.205

2.  Direction of transcription of a regulatory gene in E. coli.

Authors:  J H Miller; J Beckwith; B Muller-Hill
Journal:  Nature       Date:  1968-12-28       Impact factor: 49.962

3.  The non-linear relationship between the enzyme activity and structural protein concentration of thiogalactoside transacetylase of E. coli.

Authors:  C A Michels; D Zipser
Journal:  Biochem Biophys Res Commun       Date:  1969-02-21       Impact factor: 3.575

4.  Mutants that make more lac repressor.

Authors:  B Müller-Hill; L Crapo; W Gilbert
Journal:  Proc Natl Acad Sci U S A       Date:  1968-04       Impact factor: 11.205

5.  Mutational alteration of the maximal level of Lac operon expression.

Authors:  J Scaife; J R Beckwith
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1966

6.  Evidence for two sites for initiation of gene expression in the tryptophan operon of Salmonella typhimurium.

Authors:  R H Bauerle; P Margolin
Journal:  J Mol Biol       Date:  1967-06-28       Impact factor: 5.469

7.  The ribonuclease activity of crystallized pancreatic deoxyribonuclease.

Authors:  S B Zimmerman; D Sandeen
Journal:  Anal Biochem       Date:  1966-02       Impact factor: 3.365

8.  A membrane-filter technique for the detection of complementary DNA.

Authors:  D T Denhardt
Journal:  Biochem Biophys Res Commun       Date:  1966-06-13       Impact factor: 3.575

9.  Evidence for an altered operator specificity: catabolite repression control of the leucine operon in Salmonella typhimurium.

Authors:  S B Friedman; P Margolin
Journal:  J Bacteriol       Date:  1968-06       Impact factor: 3.490

10.  Catabolite-insensitive revertants of lac promoter mutants.

Authors:  A E Silverstone; R R Arditti; B Magasanik
Journal:  Proc Natl Acad Sci U S A       Date:  1970-07       Impact factor: 11.205
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  2 in total

1.  R-factor mutant capable of specifying hypersynthesis of penicillinase.

Authors:  Y Odakura; H Hashimoto; S Mitsuhashi
Journal:  J Bacteriol       Date:  1974-12       Impact factor: 3.490

2.  Discontinuous synthesis of lac messenger ribonucleic acid in a mutant of Escherichia coli with a new lac promoter.

Authors:  J Bruenn; W Kane
Journal:  J Bacteriol       Date:  1976-03       Impact factor: 3.490
  2 in total

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