Literature DB >> 7667881

Protein design: novel metal-binding sites.

L Regan1.   

Abstract

In natural proteins, metal ions play a variety of roles, including nucleophilic catalysis, electron transfer and the stabilization of protein structure. The de novo design of metal-binding sites is therefore an attractive means by which to impart proteins with novel properties and activities.

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Year:  1995        PMID： 7667881     DOI： 10.1016/s0968-0004(00)89044-1

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  32 in total

1.  Contribution of proton linkage to the thermodynamic stability of the major cold-shock protein of Escherichia coli CspA.

Authors:  S A Petrosian; G I Makhatadze
Journal:  Protein Sci       Date:  2000-02       Impact factor: 6.725

2.  Rational design of nascent metalloenzymes.

Authors:  D E Benson; M S Wisz; H W Hellinga
Journal:  Proc Natl Acad Sci U S A       Date:  2000-06-06       Impact factor: 11.205

3.  Ultrastructural characterization of peptide-induced membrane fusion and peptide self-assembly in the lipid bilayer.

Authors:  A S Ulrich; W Tichelaar; G Förster; O Zschörnig; S Weinkauf; H W Meyer
Journal:  Biophys J       Date:  1999-08       Impact factor: 4.033

4.  Soft metal ions, Cd(II) and Hg(II), induce triple-stranded alpha-helical assembly and folding of a de novo designed peptide in their trigonal geometries.

Authors:  X Li; K Suzuki; K Kanaori; K Tajima; A Kashiwada; H Hiroaki; D Kohda; T Tanaka
Journal:  Protein Sci       Date:  2000-07       Impact factor: 6.725

5.  Metalloprotein and metallo-DNA/RNAzyme design: current approaches, success measures, and future challenges.

Authors:  Yi Lu
Journal:  Inorg Chem       Date:  2006-12-11       Impact factor: 5.165

6.  Development of bacterium-based heavy metal biosorbents: enhanced uptake of cadmium and mercury by Escherichia coli expressing a metal binding motif.

Authors:  M Pazirandeh; B M Wells; R L Ryan
Journal:  Appl Environ Microbiol       Date:  1998-10       Impact factor: 4.792

Review 7.  On the failure of de novo-designed peptides as biocatalysts.

Authors:  M J Corey; E Corey
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-15       Impact factor: 11.205

8.  Modeling based on the structure of vicilins predicts a histidine cluster in the active site of oxalate oxidase.

Authors:  P J Gane; J M Dunwell; J Warwicker
Journal:  J Mol Evol       Date:  1998-04       Impact factor: 2.395

9.  The rational design and construction of a cuboidal iron-sulfur protein.

Authors:  C D Coldren; H W Hellinga; J P Caradonna
Journal:  Proc Natl Acad Sci U S A       Date:  1997-06-24       Impact factor: 11.205

10.  Crystal structures of the copper and nickel complexes of RNase A: metal-induced interprotein interactions and identification of a novel copper binding motif.

Authors:  R Balakrishnan; N Ramasubbu; K I Varughese; R Parthasarathy
Journal:  Proc Natl Acad Sci U S A       Date:  1997-09-02       Impact factor: 11.205
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