Literature DB >> 7667395

Defensins.

T Ganz1, R I Lehrer.   

Abstract

Defensins are a family of small cationic, antibiotic peptides that contain six cysteines in disulfide linkage. The peptides are abundant in phagocytes and small intestinal mucosa of humans and other mammals and in the hemolymph of insects. They contribute to host defense against microbes and may participate in tissue inflammation and endocrine regulation during infection. Bioengineered defensins are potentially useful as prophylactic and therapeutic agents in infections.

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Year:  1995        PMID： 7667395     DOI： 10.1016/0163-7258(94)00076-f

Source DB:  PubMed          Journal:  Pharmacol Ther        ISSN： 0163-7258            Impact factor:   12.310


  84 in total

1.  Defensins impair phagocytic killing by neutrophils in biomaterial-related infection.

Authors:  S S Kaplan; R P Heine; R L Simmons
Journal:  Infect Immun       Date:  1999-04       Impact factor: 3.441

Review 2.  Antimicrobial polypeptides in host defense of the respiratory tract.

Authors:  Tomas Ganz
Journal:  J Clin Invest       Date:  2002-03       Impact factor: 14.808

3.  Antimicrobial defensin peptides of the human ocular surface.

Authors:  R J Haynes; P J Tighe; H S Dua
Journal:  Br J Ophthalmol       Date:  1999-06       Impact factor: 4.638

4.  Interaction of antimicrobial peptide protegrin with biomembranes.

Authors:  David Gidalevitz; Yuji Ishitsuka; Adrian S Muresan; Oleg Konovalov; Alan J Waring; Robert I Lehrer; Ka Yee C Lee
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-08       Impact factor: 11.205

5.  Protegrin-1: a broad-spectrum, rapidly microbicidal peptide with in vivo activity.

Authors:  D A Steinberg; M A Hurst; C A Fujii; A H Kung; J F Ho; F C Cheng; D J Loury; J C Fiddes
Journal:  Antimicrob Agents Chemother       Date:  1997-08       Impact factor: 5.191

6.  Survival of Lactobacillus casei in the human digestive tract after consumption of fermented milk.

Authors:  Raish Oozeer; Antony Leplingard; Denis D G Mater; Agnès Mogenet; Rachel Michelin; Isabelle Seksek; Philippe Marteau; Joël Doré; Jean-Louis Bresson; Gérard Corthier
Journal:  Appl Environ Microbiol       Date:  2006-08       Impact factor: 4.792

7.  Defensins and other antimicrobial peptides at the ocular surface.

Authors:  Alison M McDermott
Journal:  Ocul Surf       Date:  2004-10       Impact factor: 5.033

8.  Innate immune peptide LL-37 displays distinct expression pattern from beta-defensins in inflamed gingival tissue.

Authors:  I Hosokawa; Y Hosokawa; H Komatsuzawa; R B Goncalves; N Karimbux; M H Napimoga; M Seki; K Ouhara; M Sugai; M A Taubman; T Kawai
Journal:  Clin Exp Immunol       Date:  2006-11       Impact factor: 4.330

Review 9.  On the physiology and pathophysiology of antimicrobial peptides.

Authors:  Roland Pálffy; Roman Gardlík; Michal Behuliak; Ludevit Kadasi; Jan Turna; Peter Celec
Journal:  Mol Med       Date:  2008-11-10       Impact factor: 6.354

10.  Comprehensive defensin assay for saliva.

Authors:  Michael S Gardner; Megan D Rowland; Amy Y Siu; Jonathan L Bundy; Diane K Wagener; James L Stephenson
Journal:  Anal Chem       Date:  2009-01-15       Impact factor: 6.986
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