Literature DB >> 7663066

Epidemiology of constipation in elderly patients. Drug utilisation and cost-containment strategies.

F A Lederle1.   

Abstract

Constipation is a common complaint among elderly people, resulting in large amounts of money being spent on laxatives. Strategies for improving patient care while reducing this expenditure include: (a) counselling patients that daily bowel movements and purging are not essential to good health, (b) greater use of nonpharmacological measures such as hydration, exercise and dietary fibre, and (c) considering safety, effectiveness and cost in the selection of a laxative. Generic preparations of psyllium and sorbitol can be recommended in this regard. The widespread use of stool softeners, magnesium hydroxide ('milk of magnesia') and stimulant laxatives is difficult to justify from the available data.

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Year:  1995        PMID: 7663066     DOI: 10.2165/00002512-199506060-00006

Source DB:  PubMed          Journal:  Drugs Aging        ISSN: 1170-229X            Impact factor:   3.923


  27 in total

1.  Dioctyl sodium sulfosuccinate- an ineffective prophylactic laxative.

Authors:  J Goodman; J Pang; A N Bessman
Journal:  J Chronic Dis       Date:  1976-01

2.  Alleviation of constipation in the elderly by dietary fiber supplementation.

Authors:  C Hull; R S Greco; D L Brooks
Journal:  J Am Geriatr Soc       Date:  1980-09       Impact factor: 5.562

3.  Cost-effective treatment of constipation in the elderly: a randomized double-blind comparison of sorbitol and lactulose.

Authors:  F A Lederle; D L Busch; K M Mattox; M J West; D M Aske
Journal:  Am J Med       Date:  1990-11       Impact factor: 4.965

Review 4.  Constipation in the elderly.

Authors:  D Harari; J H Gurwitz; K L Minaker
Journal:  J Am Geriatr Soc       Date:  1993-10       Impact factor: 5.562

5.  Chronic constipation in long stay elderly patients: a comparison of lactulose and a senna-fibre combination.

Authors:  A P Passmore; K Wilson-Davies; C Stoker; M E Scott
Journal:  BMJ       Date:  1993-09-25

6.  Safety and efficacy of a bulk laxative containing senna versus lactulose in the treatment of chronic constipation in geriatric patients.

Authors:  O Kinnunen; I Winblad; P Koistinen; J Salokannel
Journal:  Pharmacology       Date:  1993-10       Impact factor: 2.547

7.  Effect of oral dioctyl sodium sulfosuccinate on intake-output studies of human small and large intestine.

Authors:  R W Chapman; J Sillery; D D Fontana; C Matthys; D R Saunders
Journal:  Gastroenterology       Date:  1985-09       Impact factor: 22.682

8.  Effect of wheat bran on weight of stool and gastrointestinal transit time: a meta analysis.

Authors:  S A Müller-Lissner
Journal:  Br Med J (Clin Res Ed)       Date:  1988-02-27

9.  The laxative effects of lactulose in normal and constipated subjects.

Authors:  P Bass; S Dennis
Journal:  J Clin Gastroenterol       Date:  1981       Impact factor: 3.062

10.  The carry-over effect on the bowel habit in elderly long-term patients of long-term bulk-forming products containing stimulant laxative.

Authors:  O Kinnunen; J Salokannel
Journal:  Acta Med Scand       Date:  1987
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  7 in total

1.  Effectiveness of laxatives in adults.

Authors:  M Petticrew; M Rodgers; A Booth
Journal:  Qual Health Care       Date:  2001-12

2.  Economic impact of low dose polyethylene glycol 3350 plus electrolytes compared with lactulose in the management of idiopathic constipation in the UK.

Authors:  Angela H Christie; Pearl Culbert; Julian F Guest
Journal:  Pharmacoeconomics       Date:  2002       Impact factor: 4.981

3.  Direct and indirect medical costs of functional constipation: a population-based study.

Authors:  Hamid Mohaghegh Shalmani; Hamid Soori; Babak Khoshkrood Mansoori; Mohsen Vahedi; Bijan Moghimi-Dehkordi; Mohammad Amin Pourhoseingholi; Mohsen Norouzinia; Mohammad Reza Zali
Journal:  Int J Colorectal Dis       Date:  2010-10-19       Impact factor: 2.571

Review 4.  Constipation in the elderly: management strategies.

Authors:  Giancarlo Spinzi; Arnaldo Amato; Gianni Imperiali; Nicoletta Lenoci; Giovanna Mandelli; Silvia Paggi; Franco Radaelli; Natalia Terreni; Vittorio Terruzzi
Journal:  Drugs Aging       Date:  2009       Impact factor: 3.923

5.  Pilot study of pathophysiology of constipation among community diabetics.

Authors:  D Maleki; M Camilleri; D D Burton; D M Rath-Harvey; L Oenning; J H Pemberton; P A Low
Journal:  Dig Dis Sci       Date:  1998-11       Impact factor: 3.199

6.  Pharmacoeconomic Impact of Low-Dose Macrogol 3350 plus Electrolytes Compared with Lactulose in the Management of Chronic Idiopathic Constipation among Ambulant Patients in Belgium.

Authors:  Julian F Guest; Susan J Varney
Journal:  Clin Drug Investig       Date:  2004       Impact factor: 2.859

7.  Retinal insulin receptor signaling in hyperosmotic stress.

Authors:  Raju V S Rajala; Ivana Ivanovic; Ashok Kumar Dilly
Journal:  Vitam Horm       Date:  2009       Impact factor: 3.421

  7 in total

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