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Literature DB >> 7662368

Locking in stable states of gene expression: transcriptional control during Drosophila development.

Abstract

Cell fate decisions can be maintained during long periods of developmental time by stable states of gene expression. The Polycomb group and trithorax group proteins of Drosophila are key transcriptional regulators that maintain stable expression states during development. Recent advances in knowledge about individual Polycomb group and trithorax group proteins, their mechanisms of action, and potential homologs in mice and humans are contributing to a greater understanding of their roles in gene expression and development.

Entities: Gene Species

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Year: 1995 PMID： 7662368 DOI： 10.1016/0955-0674(95)80093-x

Source DB: PubMed Journal: Curr Opin Cell Biol ISSN： 0955-0674 Impact factor: 8.382

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Cited

90 in total

1. Hypomethylation promotes autonomous endosperm development and rescues postfertilization lethality in fie mutants.

Authors: R Vinkenoog; M Spielman; S Adams; R L Fischer; H G Dickinson; R J Scott
Journal: Plant Cell Date: 2000-11 Impact factor: 11.277

2. Polycomb group repression reduces DNA accessibility.

Authors: D P Fitzgerald; W Bender
Journal: Mol Cell Biol Date: 2001-10 Impact factor: 4.272

3. Site-specific recognition of a 70-base-pair element containing d(GA)(n) repeats mediates bithoraxoid polycomb group response element-dependent silencing.

Authors: J W Hodgson; B Argiropoulos; H W Brock
Journal: Mol Cell Biol Date: 2001-07 Impact factor: 4.272

4. A mutational analysis of leaf morphogenesis in Arabidopsis thaliana.

Authors: G Berná; P Robles; J L Micol
Journal: Genetics Date: 1999-06 Impact factor: 4.562

5. Mutations in Drosophila heat shock cognate 4 are enhancers of Polycomb.

Authors: R Mollaaghababa; L Sipos; S Y Tiong; O Papoulas; J A Armstrong; J W Tamkun; W Bender
Journal: Proc Natl Acad Sci U S A Date: 2001-03-27 Impact factor: 11.205

6. Functional interaction between the coactivator Drosophila CREB-binding protein and ASH1, a member of the trithorax group of chromatin modifiers.

Authors: F Bantignies; R H Goodman; S M Smolik
Journal: Mol Cell Biol Date: 2000-12 Impact factor: 4.272

Locking in stable states of gene expression: transcriptional control during Drosophila development.

1. Hypomethylation promotes autonomous endosperm development and rescues postfertilization lethality in fie mutants.

2. Polycomb group repression reduces DNA accessibility.

3. Site-specific recognition of a 70-base-pair element containing d(GA)(n) repeats mediates bithoraxoid polycomb group response element-dependent silencing.

4. A mutational analysis of leaf morphogenesis in Arabidopsis thaliana.

5. Mutations in Drosophila heat shock cognate 4 are enhancers of Polycomb.

6. Functional interaction between the coactivator Drosophila CREB-binding protein and ASH1, a member of the trithorax group of chromatin modifiers.

7. The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans.

Review 8. Role of chromatin states in transcriptional memory.

Review 9. Menin, histone h3 methyltransferases, and regulation of cell proliferation: current knowledge and perspective.

10. RNA-DNA strand exchange by the Drosophila Polycomb complex PRC2.