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Literature DB >> 7662298

Production of brefeldin-A.

T G McCloud¹, M P Burns, F D Majadly, G M Muschik, D A Miller, K K Poole, J M Roach, J T Ross, W B Lebherz.

Abstract

Fermentation conditions are described for the production of the antitumor antibiotic 7-(S)-brefeldin-A (brefeldin-A) in liquid culture by Eupenicillium brefeldianum, (B.Dodge) Stolk and Scott, ATCC 58665. An analytical hplc method was developed which allowed rapid quantitation of the compound during fermentation. A kilogram of brefeldin-A was isolated from a fermentation at the 6800-liter scale.

Entities: Chemical Species

Mesh：

Substances：

Year: 1995 PMID： 7662298 DOI： 10.1007/bf01570006

Source DB: PubMed Journal: J Ind Microbiol ISSN： 0169-4146

12 in total

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Authors: V BETINA; P NEMEC; J DOBIAS; Z BARATH
Journal: Folia Microbiol (Praha) Date: 1962-11 Impact factor: 2.099

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Journal: Nature Date: 1958-04-12 Impact factor: 49.962

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Authors: W R Abraham; H A Arfmann
Journal: Planta Med Date: 1992-10 Impact factor: 3.352

Review 4. Thyroid-stimulating hormone: biosynthesis, cell biology, and bioactivity.

Authors: J A Magner
Journal: Endocr Rev Date: 1990-05 Impact factor: 19.871

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Authors: K Mizuno; M Tsujino; M Takada; M Hayashi; K Atsumi
Journal: J Antibiot (Tokyo) Date: 1974-10 Impact factor: 2.649

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Authors: H P Weber; D Hauser; H P Sigg
Journal: Helv Chim Acta Date: 1971 Impact factor: 2.164

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Authors: M Sunagawa; T Ohta; S Nozoe
Journal: J Antibiot (Tokyo) Date: 1983-01 Impact factor: 2.649

8. Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines.

Authors: A Monks; D Scudiero; P Skehan; R Shoemaker; K Paull; D Vistica; C Hose; J Langley; P Cronise; A Vaigro-Wolff
Journal: J Natl Cancer Inst Date: 1991-06-05 Impact factor: 13.506

9. Eupenifeldin, a novel cytotoxic bistropolone from Eupenicillium brefeldianum.

Authors: F Mayerl; Q Gao; S Huang; S E Klohr; J A Matson; D R Gustavson; D M Pirnik; R L Berry; C Fairchild; W C Rose
Journal: J Antibiot (Tokyo) Date: 1993-07 Impact factor: 2.649

10. Brefeldin A inhibits oligosaccharide processing of glycoproteins in mouse hypothyroid pituitary tissue at several subcellular sites.

Authors: V S Perkel; Y Miura; J A Magner
Journal: Proc Soc Exp Biol Med Date: 1989-03

6 in total

1. Cell wall accumulation of fluorescent proteins derived from a trans-Golgi cisternal membrane marker and paramural bodies in interdigitated Arabidopsis leaf epidermal cells.

Authors: Kae Akita; Megumi Kobayashi; Mayuko Sato; Natsumaro Kutsuna; Takashi Ueda; Kiminori Toyooka; Noriko Nagata; Seiichiro Hasezawa; Takumi Higaki
Journal: Protoplasma Date: 2016-03-09 Impact factor: 3.356

6. cis-Golgi proteins accumulate near the ER exit sites and act as the scaffold for Golgi regeneration after brefeldin A treatment in tobacco BY-2 cells.

Authors: Yoko Ito; Tomohiro Uemura; Keiko Shoda; Masaru Fujimoto; Takashi Ueda; Akihiko Nakano
Journal: Mol Biol Cell Date: 2012-06-27 Impact factor: 4.138