Literature DB >> 7650216

Genotyping of hepatitis C virus in South Africa.

H E Smuts1, J Kannemeyer.   

Abstract

The six major hepatitis C virus genotypes were investigated by using samples from 79 seropositive and PCR-positive blood donors from three different regions of South Africa as well as 9 patients with chronic renal failure, 19 with liver disease, and 23 with hemophilia. PCR products of the genome were typed by restriction fragment length polymorphic analysis by RsaI-HaeIII and MvaI-HinfI double digestion. Type 5 occurred in 40% of this population group; type 1 occurred in 33%; and types 2, 3, and 4 were found in 13.8, 7.7, and 2.3%, respectively.

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Year:  1995        PMID: 7650216      PMCID: PMC228247          DOI: 10.1128/jcm.33.6.1679-1681.1995

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  25 in total

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3.  Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

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Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205

5.  Hepatitis C virus infection is associated with the development of hepatocellular carcinoma.

Authors:  I Saito; T Miyamura; A Ohbayashi; H Harada; T Katayama; S Kikuchi; Y Watanabe; S Koi; M Onji; Y Ohta
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6.  An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis.

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7.  Full-length sequence of a hepatitis C virus genome having poor homology to reported isolates: comparative study of four distinct genotypes.

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10.  Typing hepatitis C virus by polymerase chain reaction with type-specific primers: application to clinical surveys and tracing infectious sources.

Authors:  H Okamoto; Y Sugiyama; S Okada; K Kurai; Y Akahane; Y Sugai; T Tanaka; K Sato; F Tsuda; Y Miyakawa
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  19 in total

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Journal:  Arch Virol       Date:  1996       Impact factor: 2.574

7.  Hepatitis C virus genotype 5a subgenomic replicons for evaluation of direct-acting antiviral agents.

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Review 9.  Epidemiology and treatment of hepatitis C genotypes 5 and 6.

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