Literature DB >> 7636896

Conservative treatment of early-stage breast cancer in a medically indigent population.

R G Smith1, J C Landry, L L Hughes, M R Moore, M J Lynn, L W Davis, T Styblo, I R Crocker, W C Wood.   

Abstract

The compliance with a program of breast-conservation treatment for early-stage breast cancer and the results of that treatment among women treated between January 1983 and January 1992 was investigated in a large inner-city public hospital serving a primarily black population. Medical records and charts were reviewed for 25 consecutive patients with stage I and II breast cancer seen in consultation in the radiation oncology department. Of those 25 patients, 20 underwent lumpectomy and radiation therapy. Survival, disease-free survival, and local recurrence-free survival were computed using the Kaplan-Meier method. Compliance was evaluated based on time to complete the prescribed course of radiotherapy after a lumpectomy. Five-year local recurrence-free survival for stage I and II patients was 95% (confidence interval [CI]: 71% to 99%). Five-year overall survival for stage II patients was 71% (CI: 31% to 92%), and disease-free survival was 74% (CI: 36% to 91%). This study demonstrates that a program of breast-conservation treatment for early-stage breast cancer can be implemented with good results, excellent treatment compliance, and 100% follow-up in a population of medically indigent women.

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Year:  1995        PMID: 7636896      PMCID: PMC2607850     

Source DB:  PubMed          Journal:  J Natl Med Assoc        ISSN: 0027-9684            Impact factor:   1.798


  11 in total

1.  Mastectomy versus breast-conserving therapy in the treatment of stage I and II carcinoma of the breast: a randomized trial at the National Cancer Institute.

Authors:  A S Lichter; M E Lippman; D N Danforth; T d'Angelo; S M Steinberg; E deMoss; H D MacDonald; C M Reichert; M Merino; S M Swain
Journal:  J Clin Oncol       Date:  1992-06       Impact factor: 44.544

2.  Conservative surgery and radiation therapy in breast carcinoma: local recurrence and prognostic implications.

Authors:  B G Haffty; N B Goldberg; D Fischer; C McKhann; M Beinfield; J B Weissberg; D Carter; W Gerald
Journal:  Int J Radiat Oncol Biol Phys       Date:  1989-10       Impact factor: 7.038

3.  Analysis of local-regional relapses in patients with early breast cancers treated by excision and radiotherapy: experience of the Institut Gustave-Roussy.

Authors:  D H Clarke; M G Lê; D Sarrazin; M J Lacombe; F Fontaine; J P Travagli; F May-Levin; G Contesso; R Arriagada
Journal:  Int J Radiat Oncol Biol Phys       Date:  1985-01       Impact factor: 7.038

4.  Local recurrence after breast-conserving surgery and radiotherapy. Frequency, time course, and prognosis.

Authors:  J M Kurtz; R Amalric; H Brandone; Y Ayme; J Jacquemier; J C Pietra; D Hans; J F Pollet; C Bressac; J M Spitalier
Journal:  Cancer       Date:  1989-05-15       Impact factor: 6.860

5.  Excisional biopsy, axillary node dissection and definitive radiotherapy for Stages I and II breast cancer.

Authors:  B F Danoff; T F Pajak; L J Solin; R L Goodman
Journal:  Int J Radiat Oncol Biol Phys       Date:  1985-03       Impact factor: 7.038

6.  Radiation therapy as initial treatment for early stage cancer of the breast without mastectomy.

Authors:  L R Prosnitz; I S Goldenberg; R A Packard; M B Levene; J Harris; S Hellman; P E Wallner; L W Brady; C M Mansfield; S Kramer
Journal:  Cancer       Date:  1977-02       Impact factor: 6.860

Review 7.  Definitive irradiation for early stage breast cancer: The University of Pennsylvania experience.

Authors:  L J Solin; B Fowble; K L Martz; R L Goodman
Journal:  Int J Radiat Oncol Biol Phys       Date:  1988-02       Impact factor: 7.038

8.  Prognostic factors of breast recurrence in the conservative management of early breast cancer: a 25-year follow-up.

Authors:  A Fourquet; F Campana; B Zafrani; V Mosseri; P Vielh; J C Durand; J R Vilcoq
Journal:  Int J Radiat Oncol Biol Phys       Date:  1989-10       Impact factor: 7.038

9.  The impact of tumor size and histology on local control after breast-conserving therapy.

Authors:  H Bartelink; J H Borger; J A van Dongen; J L Peterse
Journal:  Radiother Oncol       Date:  1988-04       Impact factor: 6.280

10.  Five-year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in the treatment of breast cancer.

Authors:  B Fisher; M Bauer; R Margolese; R Poisson; Y Pilch; C Redmond; E Fisher; N Wolmark; M Deutsch; E Montague
Journal:  N Engl J Med       Date:  1985-03-14       Impact factor: 91.245

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  4 in total

1.  Black and white patients fare equally well when treated with postlumpectomy radiotherapy.

Authors:  Stuart H Burri; Jerome C Landry; H James Norton; Lawrence W Davis
Journal:  J Natl Med Assoc       Date:  2004-07       Impact factor: 1.798

2.  Patient compliance is critical for equivalent clinical outcomes for breast cancer treated by breast-conservation therapy.

Authors:  B D Li; W A Brown; F L Ampil; G V Burton; H Yu; J C McDonald
Journal:  Ann Surg       Date:  2000-06       Impact factor: 12.969

3.  Breast conservation is an effective option in Black, medically indigent patients.

Authors:  Stuart H Burri; Jerome C Landry; Lawrence W Davis
Journal:  J Natl Med Assoc       Date:  2002-06       Impact factor: 1.798

4.  Factors associated with contralateral preventive mastectomy.

Authors:  Danny Yakoub; Eli Avisar; Tulay Koru-Sengul; Feng Miao; Stacey L Tannenbaum; Margaret M Byrne; Frederick Moffat; Alan Livingstone; Dido Franceschi
Journal:  Breast Cancer (Dove Med Press)       Date:  2015-01-07
  4 in total

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