Literature DB >> 12078926

Breast conservation is an effective option in Black, medically indigent patients.

Stuart H Burri1, Jerome C Landry, Lawrence W Davis.   

Abstract

The purpose of the study was to evaluate the efficacy of lumpectomy and postoperative radiotherapy in an African-American, medically indigent population. From 1980 through 1996, a retrospective chart review was undertaken of the patients treated with radiotherapy after lumpectomy at an inner city hospital, whose patients are primarily African American and uninsured. One hundred and one patients were treated with breast conservation during this time. Of those, 72 were African American and with invasive carcinoma. The data were analyzed using JMP IN (SAS Institute). The study found that African-American patients with invasive carcinoma had 95.2% local control at 5 years and 87.9% at 10 years. The disease-free survival was 84.6% at 5 years and 65.3% at 10 years. Patients that received less than 50 Gray to the tumor bed had inferior local control, disease-free survival, and overall survival (p < 0.0001 for all three). The 5-year and 10-year local control for DCIS, in a limited number of patients, was 95.2%. We conclude that lumpectomy followed by radiotherapy is an effective treatment strategy in the high-risk population of African-American, medically indigent patients. The local control and disease-free survival compare favorably to published controls in this traditionally high-risk patient population.

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Year:  2002        PMID: 12078926      PMCID: PMC2594396     

Source DB:  PubMed          Journal:  J Natl Med Assoc        ISSN: 0027-9684            Impact factor:   1.798


  20 in total

1.  The influence of black race and socioeconomic status on the use of breast-conserving surgery for Medicare beneficiaries.

Authors:  T A Michalski; A B Nattinger
Journal:  Cancer       Date:  1997-01-15       Impact factor: 6.860

2.  Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-17.

Authors:  B Fisher; J Dignam; N Wolmark; E Mamounas; J Costantino; W Poller; E R Fisher; D L Wickerham; M Deutsch; R Margolese; N Dimitrov; M Kavanah
Journal:  J Clin Oncol       Date:  1998-02       Impact factor: 44.544

3.  Race and clinical outcome in breast cancer in a series with long-term follow-up evaluation.

Authors:  R Heimann; D Ferguson; C Powers; D Suri; R R Weichselbaum; S Hellman
Journal:  J Clin Oncol       Date:  1997-06       Impact factor: 44.544

4.  Prognosis among African-American women and white women with lymph node negative breast carcinoma: findings from two randomized clinical trials of the National Surgical Adjuvant Breast and Bowel Project (NSABP).

Authors:  J J Dignam; C K Redmond; B Fisher; J P Costantino; B K Edwards
Journal:  Cancer       Date:  1997-07-01       Impact factor: 6.860

5.  Importance of race on breast cancer survival.

Authors:  G H Lyman; N M Kuderer; S L Lyman; C E Cox; D Reintgen; P Baekey
Journal:  Ann Surg Oncol       Date:  1997-01       Impact factor: 5.344

6.  Race and survival from breast cancer: based on Cancer and Leukemia Group B trial 8541.

Authors:  M Roach; C Cirrincione; D Budman; D Hayes; D Berry; J Younger; R Hart; I C Henderson
Journal:  Cancer J Sci Am       Date:  1997 Mar-Apr

7.  Influence of socioeconomic and cultural factors on racial differences in late-stage presentation of breast cancer.

Authors:  D R Lannin; H F Mathews; J Mitchell; M S Swanson; F H Swanson; M S Edwards
Journal:  JAMA       Date:  1998-06-10       Impact factor: 56.272

8.  Infiltrating ductal carcinoma of the breast: the survival impact of race.

Authors:  M J Edwards; J W Gamel; W P Vaughan; W R Wrightson
Journal:  J Clin Oncol       Date:  1998-08       Impact factor: 44.544

9.  Breast cancer. Is ethnicity an independent prognostic factor for survival?

Authors:  P Perkins; C D Cooksley; J D Cox
Journal:  Cancer       Date:  1996-09-15       Impact factor: 6.860

10.  Breast carcinoma tumor characteristics in black and white women.

Authors:  J G Elmore; V M Moceri; D Carter; E B Larson
Journal:  Cancer       Date:  1998-12-15       Impact factor: 6.860

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  1 in total

1.  Black and white patients fare equally well when treated with postlumpectomy radiotherapy.

Authors:  Stuart H Burri; Jerome C Landry; H James Norton; Lawrence W Davis
Journal:  J Natl Med Assoc       Date:  2004-07       Impact factor: 1.798

  1 in total

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