Literature DB >> 7626574

Retinal detachment and herpesvirus retinitis in patients with AIDS.

J G Dowler1, H M Towler, S M Mitchell, R J Cooling, S L Lightman.   

Abstract

BACKGROUND: The prolongation of survival of patients with herpesvirus retinitis and AIDS has been associated with a rise in the incidence of retinal detachment. In such cases, however, retinal reattachment may be difficult to achieve, and postoperative visual acuity may be poor despite anatomically successful surgery.
METHODS: In order to examine factors affecting the visual outcome of surgery, a retrospective review of 29 patients with retinal detachment, herpesvirus retinitis, and AIDS was performed. Retinal reattachment surgery (32 procedures) or prophylactic laser demarcation (five procedures) was performed in 28 eyes of 23 patients.
RESULTS: The macula was attached in 23/28 (82%) eyes at the last outpatient visit. Best postoperative visual acuity (median 6/18, range 6/6-hand movements) was significantly greater than final postoperative acuity (median counting fingers, range 6/6-no perception of light) (Wilcoxon sign rank test, p = 0.003), and was retained for a median of 3 months (1-91 weeks) after surgery. Poor visual outcome as evidenced by submedian final visual acuity was invariably associated with persistence of macular detachment, and significantly associated with the occurrence of optic atrophy (odds ratio = 5, p = 0.02).
CONCLUSION: Retinal reattachment surgery appears justified in patients with herpesvirus retinitis and AIDS, but postoperative visual deterioration may occur in association with optic atrophy.

Entities:  

Mesh:

Year:  1995        PMID: 7626574      PMCID: PMC505169          DOI: 10.1136/bjo.79.6.575

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  21 in total

1.  The effect of topically applied fluorescein on fluorescent monoclonal antibodies in the diagnosis of chlamydial conjunctivitis.

Authors:  M P Vrabec; P J McCanna
Journal:  Ann Ophthalmol       Date:  1988-11

2.  Cytomegalovirus retinitis and acquired immunodeficiency syndrome.

Authors:  D A Jabs; C Enger; J G Bartlett
Journal:  Arch Ophthalmol       Date:  1989-01

3.  The spectrum of optic nerve disease in human immunodeficiency virus infection.

Authors:  K E Winward; L M Hamed; J S Glaser
Journal:  Am J Ophthalmol       Date:  1989-04-15       Impact factor: 5.258

4.  Severe visual loss related to isolated peripapillary retinal and optic nerve head cytomegalovirus infection.

Authors:  J G Gross; A A Sadun; C A Wiley; W R Freeman
Journal:  Am J Ophthalmol       Date:  1989-12-15       Impact factor: 5.258

5.  A masked prospective evaluation of outcome parameters for cytomegalovirus-related retinal detachment surgery in patients with acquired immune deficiency syndrome.

Authors:  B D Kuppermann; M Flores-Aguilar; J I Quiceno; E V Capparelli; L Levi; D Munguia; W R Freeman
Journal:  Ophthalmology       Date:  1994-01       Impact factor: 12.079

6.  Presumed varicella zoster retinitis in immunocompromised patients.

Authors:  D A Jabs; A P Schachat; R Liss; D L Knox; R G Michels
Journal:  Retina       Date:  1987       Impact factor: 4.256

7.  Management of retinal detachment associated with CMV retinitis in AIDS patients.

Authors:  E L Chuang; J L Davis
Journal:  Eye (Lond)       Date:  1992       Impact factor: 3.775

8.  Improved visual results after surgical repair of cytomegalovirus-related retinal detachments.

Authors:  J I Lim; C Enger; J A Haller; P A Campochiaro; T A Meredith; S de Bustros; J P Dunn; D A Jabs
Journal:  Ophthalmology       Date:  1994-02       Impact factor: 12.079

9.  The question of ocular tolerance to intravitreal liquid silicone. A long-term analysis.

Authors:  C Chan; E Okun
Journal:  Ophthalmology       Date:  1986-05       Impact factor: 12.079

10.  Acute retinal necrosis neuropathy. Clinical profile and surgical therapy.

Authors:  R C Sergott; R Anand; J B Belmont; D H Fischer; T M Bosley; P J Savino
Journal:  Arch Ophthalmol       Date:  1989-05
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  2 in total

1.  Retinal detachment in AIDS: long-term results after repair with silicone oil.

Authors:  A R Irvine; L Lonn; D Schwartz; M Zarbin; F Ballesteros; S Kroll
Journal:  Br J Ophthalmol       Date:  1997-03       Impact factor: 4.638

2.  Outcomes of cytomegalovirus retinitis-related retinal detachment surgery in acquired immunodeficiency syndrome patients in an Asian population.

Authors:  John X Wong; Elizabeth P Wong; Stephen C Teoh
Journal:  BMC Ophthalmol       Date:  2014-11-27       Impact factor: 2.209

  2 in total

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