Literature DB >> 7626209

[Antidepressant active constituents in the roots of Morinda officinalis How].

C Cui1, M Yang, Z Yao, B Cao, Z Luo, Y Xu, Y Chen.   

Abstract

Five compounds having antidepressant activities have been isolated from the roots of Morinda officinalis, a Chinese traditional Yang-tonic drug. These compounds were identified as succinic acid (1), nystose (2), 1F-fructofuranosylnystose (3), inulin-type hexasaccharide (4) and heptasaccharide (5) by chemical and spectroscopic methods. All of the compounds are isolated from the species of genus Morinda for the first time.

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Year:  1995        PMID: 7626209

Source DB:  PubMed          Journal:  Zhongguo Zhong Yao Za Zhi        ISSN: 1001-5302


  5 in total

1.  Effects of the Salt-Processing Method on the Pharmacokinetics and Tissue Distribution of Orally Administered Morinda officinalis How. Extract.

Authors:  Ji Shi; Xiaohang Ren; Jia Wang; Xiaofeng Wei; Bonan Liu; Tianzhu Jia
Journal:  J Anal Methods Chem       Date:  2020-02-11       Impact factor: 2.193

Review 2.  Translational Informatics for Natural Products as Antidepressant Agents.

Authors:  Rajeev K Singla; Shikha Joon; Li Shen; Bairong Shen
Journal:  Front Cell Dev Biol       Date:  2022-01-20

3.  Morinda officinalis oligosaccharides increase serotonin in the brain and ameliorate depression via promoting 5-hydroxytryptophan production in the gut microbiota.

Authors:  Zheng-Wei Zhang; Chun-Sheng Gao; Heng Zhang; Jian Yang; Ya-Ping Wang; Li-Bin Pan; Hang Yu; Chi-Yu He; Hai-Bin Luo; Zhen-Xiong Zhao; Xin-Bo Zhou; Yu-Li Wang; Jie Fu; Pei Han; Yu-Hui Dong; Gang Wang; Song Li; Yan Wang; Jian-Dong Jiang; Wu Zhong
Journal:  Acta Pharm Sin B       Date:  2022-03-03       Impact factor: 14.903

Review 4.  Neuroprotective effects of Morinda officinalis How.: Anti-inflammatory and antioxidant roles in Alzheimer's disease.

Authors:  Yi Zhang; Meng Zhang
Journal:  Front Aging Neurosci       Date:  2022-09-08       Impact factor: 5.702

5.  Phenotypic, chemical component and molecular assessment of genetic diversity and population structure of Morinda officinalis germplasm.

Authors:  Zhenhua Luo; Zien Chen; Mengyun Liu; Li Yang; Zhimin Zhao; Depo Yang; Ping Ding
Journal:  BMC Genomics       Date:  2022-08-19       Impact factor: 4.547

  5 in total

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