Literature DB >> 7623040

Gamma-indomycinone, a new pluramycin metabolite from a deep-sea derived actinomycete.

R W Schumacher1, B S Davidson, D A Montenegro, V S Bernan.   

Abstract

A new member of the pluramycin class of antibiotics, gamma-indomycinone [1], has been isolated along with the known compounds rubiflavinone C-1 [2] and beta-indomycinone [3] from the culture broth of a Streptomyces sp. obtained from a deep-sea sediment core. Each compound is composed of an anthraquinone-gamma-pyrone nucleus, but bears a different side-chain. Compounds 2 and 3 were identified by comparison of their spectral data with published data, while gamma-indomycinone [1] was characterized using 1H-nmr and mass spectrometry.

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Year:  1995        PMID: 7623040     DOI: 10.1021/np50118a024

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  5 in total

Review 1.  Culturability and secondary metabolite diversity of extreme microbes: expanding contribution of deep sea and deep-sea vent microbes to natural product discovery.

Authors:  Robin K Pettit
Journal:  Mar Biotechnol (NY)       Date:  2010-05-01       Impact factor: 3.619

2.  Saliniquinones A-F, New Members of the Highly Cytotoxic Anthraquinone-γ-Pyrones from the Marine Actinomycete Salinispora arenicola.

Authors:  Brian T Murphy; Tadigoppula Narender; Christopher A Kauffman; Matthew Woolery; Paul R Jensen; William Fenical
Journal:  Aust J Chem       Date:  2010-06-01       Impact factor: 1.321

3.  Saliniquinone Derivatives, Saliniquinones G-I and Heraclemycin E, from the Marine Animal-Derived Nocardiopsis aegyptia HDN19-252.

Authors:  Luning Zhou; Xuedong Chen; Chunxiao Sun; Yimin Chang; Xiaofei Huang; Tianjiao Zhu; Guojian Zhang; Qian Che; Dehai Li
Journal:  Mar Drugs       Date:  2021-10-14       Impact factor: 5.118

4.  Elucidation of the di-c-glycosylation steps during biosynthesis of the antitumor antibiotic, kidamycin.

Authors:  Kyung Taek Heo; Byeongsan Lee; Jae-Hyuk Jang; Young-Soo Hong
Journal:  Front Bioeng Biotechnol       Date:  2022-08-25

5.  Shellmycin A-D, Novel Bioactive Tetrahydroanthra-γ-Pyrone Antibiotics from Marine Streptomyces sp. Shell-016.

Authors:  Yong Han; Yan Wang; Yuehan Yang; Haotong Chen
Journal:  Mar Drugs       Date:  2020-01-16       Impact factor: 5.118

  5 in total

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