Literature DB >> 762169

Studies on the destruction of adrenal and testicular cytochrome P-450 by spironolactone. Requirement for the 7alpha-thio group and evidence for the loss of the heme and apoproteins of cytochrome P-450.

R H Menard, T M Guenthner, H Kon, J R Gillette.   

Abstract

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Year:  1979        PMID： 762169

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


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  10 in total

1.  Spironolactone, a possible selective androgen receptor modulator, should be used with caution in patients with metastatic carcinoma of the prostate.

Authors:  Santhanam Sundar; Peter D Dickinson
Journal:  BMJ Case Rep       Date:  2012-02-25

Review 2.  How actual is the treatment with antiandrogen alone in patients with polycystic ovary syndrome?

Authors:  E Diamanti-Kandarakis
Journal:  J Endocrinol Invest       Date:  1998-10       Impact factor: 4.256

3.  Difference in metabolic profile of potassium canrenoate and spironolactone in the rat: mutagenic metabolites unique to potassium canrenoate.

Authors:  C S Cook; C L Hauswald; G L Schoenhard; C E Piper; A Patel; F M Radzialowski; J D Hribar; W Aksamit; P Finnegan; R H Bible
Journal:  Arch Toxicol       Date:  1988-01       Impact factor: 5.153

4.  Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression.

Authors:  K S Lown; D G Bailey; R J Fontana; S K Janardan; C H Adair; L A Fortlage; M B Brown; W Guo; P B Watkins
Journal:  J Clin Invest       Date:  1997-05-15       Impact factor: 14.808

5.  Contrasting effects of eplerenone and spironolactone on adrenal cell steroidogenesis.

Authors:  P Ye; T Yamashita; D M Pollock; H Sasano; W E Rainey
Journal:  Horm Metab Res       Date:  2008-09-25       Impact factor: 2.936

6.  Effects of repeated administration of potassium canrenoate (SC-14266) on serum gonadotrophin, prolactin, testosterone and progesterone in male rats.

Authors:  T Muraki; T Nakadate; K Kubota; Y Tokunaga; R Kato
Journal:  Experientia       Date:  1980-06-15

Review 7.  The management of patients with polycystic ovary syndrome.

Authors:  Channa N Jayasena; Stephen Franks
Journal:  Nat Rev Endocrinol       Date:  2014-07-15       Impact factor: 43.330

Review 8.  Oral Spironolactone for Acne Vulgaris in Adult Females: A Hybrid Systematic Review.

Authors:  Alison M Layton; E Anne Eady; Heather Whitehouse; James Q Del Rosso; Zbys Fedorowicz; Esther J van Zuuren
Journal:  Am J Clin Dermatol       Date:  2017-04       Impact factor: 7.403

Review 9.  Mineralocorticoid receptor antagonists.

Authors:  Hari Krishnan Parthasarathy; Thomas M MacDonald
Journal:  Curr Hypertens Rep       Date:  2007-03       Impact factor: 4.592

10.  Chemical suppression of steroidogenesis.

Authors:  H D Colby
Journal:  Environ Health Perspect       Date:  1981-04       Impact factor: 9.031
  10 in total

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