Literature DB >> 7619109

Insulin-like growth factors and cancer.

D LeRoith1, R Baserga, L Helman, C T Roberts.   

Abstract

The insulin-like growth factor (IGF) family of peptides, binding proteins, and receptors are important for normal human growth and development and are involved in the specialized functions of most physiologic systems. Most members of the IGF system are expressed by different cancer cells and may play an important role in the propagation of these malignancies. New therapies aimed at modulating various components of the IGF system could affect the progression and metastasis of cancer.

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Year:  1995        PMID： 7619109     DOI： 10.7326/0003-4819-122-1-199501010-00009

Source DB:  PubMed          Journal:  Ann Intern Med        ISSN： 0003-4819            Impact factor:   25.391


  75 in total

Review 1.  The role of circulating IGF-I: lessons from human and animal models.

Authors:  Shoshana Yakar; Yiping Wu; Jennifer Setser; Clifford J Rosen
Journal:  Endocrine       Date:  2002-12       Impact factor: 3.633

2.  Plasma levels of insulin-like growth factor-1 and insulin-like growth factor binding protein-3 in women with cervical neoplasia.

Authors:  Si Won Lee; Soo Yoon Lee; Sa Ra Lee; Woong Ju; Seung Cheol Kim
Journal:  J Gynecol Oncol       Date:  2010-09-28       Impact factor: 4.401

Review 3.  Update in new anabolic therapies for osteoporosis.

Authors:  Ernesto Canalis
Journal:  J Clin Endocrinol Metab       Date:  2010-04       Impact factor: 5.958

Review 4.  The insulin-like growth factor system and colorectal cancer: clinical and experimental evidence.

Authors:  M Davies; S Gupta; G Goldspink; M Winslet
Journal:  Int J Colorectal Dis       Date:  2005-06-16       Impact factor: 2.571

Review 5.  New treatment modalities in osteoporosis.

Authors:  Ernesto Canalis
Journal:  Endocr Pract       Date:  2010 Sep-Oct       Impact factor: 3.443

6.  Development of targeted therapy for a broad spectrum of solid tumors mediated by a double promoter plasmid expressing diphtheria toxin under the control of IGF2-P4 and IGF2-P3 regulatory sequences.

Authors:  Doron Amit; Sagi Tamir; Abraham Hochberg
Journal:  Int J Clin Exp Med       Date:  2013-01-26

7.  Serum and tissue level of insulin-like growth factor-I (IGF-I) and IGF-I binding proteins as an index of pancreatitis and pancreatic cancer.

Authors:  Ewa Karna; Arkadiusz Surazynski; Kazimierz Orłowski; Joanna Łaszkiewicz; Zbigniew Puchalski; Piotr Nawrat; Jerzy Pałka
Journal:  Int J Exp Pathol       Date:  2002-10       Impact factor: 1.925

8.  Race/ethnic variation in serum levels of IGF-I and IGFBP-3 in US adults.

Authors:  David Berrigan; Nancy Potischman; Kevin W Dodd; Stephen D Hursting; Jackie Lavigne; J Carl Barrett; Rachel Ballard-Barbash
Journal:  Growth Horm IGF Res       Date:  2008-09-21       Impact factor: 2.372

9.  Role of the insulin-like growth factor I/insulin receptor substrate 1 axis in Rad51 trafficking and DNA repair by homologous recombination.

Authors:  Joanna Trojanek; Thu Ho; Luis Del Valle; Michal Nowicki; Jin Ying Wang; Adam Lassak; Francesca Peruzzi; Kamel Khalili; Tomasz Skorski; Krzysztof Reiss
Journal:  Mol Cell Biol       Date:  2003-11       Impact factor: 4.272

10.  Insulin therapy and the risk of colorectal cancer in patients with type 2 diabetes: a meta-analysis of observational studies.

Authors:  Wu-jie Bu; Lei Song; Dan-yi Zhao; Bing Guo; Jing Liu
Journal:  Br J Clin Pharmacol       Date:  2014-08       Impact factor: 4.335
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