Literature DB >> 7613029

Localization of two mouse genes encoding the protein tyrosine kinase receptor-related protein RYK.

N M Gough1, S Rakar, C M Hovens, A Wilks.   

Abstract

We have mapped the gene encoding the murine RYK growth factor receptor protein tyrosine kinase by genetic linkage analysis with recombinant inbred strains of mouse. Two distinct Ryk loci (Ryk-1 and Ryk-2) were identified. Ryk-1 mapped to Chromosome (Chr) 9, whereas Ryk-2 mapped to Chr 12. A similar arrangement of RYK-related loci was previously determined in the human. Synteny has already been established between murine Chr 9 in the region of Ryk-1, and human chromosome 3q11-12, the location of the human RYK-1 gene. However, the Ryk-2/RYK-2 loci on murine Chr 12 and human Chr 17p13.3 define a new region of synteny.

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Year:  1995        PMID： 7613029     DOI： 10.1007/BF00352411

Source DB:  PubMed          Journal:  Mamm Genome        ISSN： 0938-8990            Impact factor:   2.957


  10 in total

1.  RYK, a receptor tyrosine kinase-related molecule with unusual kinase domain motifs.

Authors:  C M Hovens; S A Stacker; A C Andres; A G Harpur; A Ziemiecki; A F Wilks
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-15       Impact factor: 11.205

2.  Mapping the adrenal lipid depletion gene of the AKR/J mouse strain.

Authors:  B A Taylor; H Meier
Journal:  Genet Res       Date:  1975-12       Impact factor: 1.588

Review 3.  Growth factor receptor tyrosine kinases.

Authors:  Y Yarden; A Ullrich
Journal:  Annu Rev Biochem       Date:  1988       Impact factor: 23.643

Review 4.  The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.

Authors:  S K Hanks; A M Quinn; T Hunter
Journal:  Science       Date:  1988-07-01       Impact factor: 47.728

5.  Sevenless, a cell-specific homeotic gene of Drosophila, encodes a putative transmembrane receptor with a tyrosine kinase domain.

Authors:  E Hafen; K Basler; J E Edstroem; G M Rubin
Journal:  Science       Date:  1987-04-03       Impact factor: 47.728

Review 6.  Protein tyrosine kinase growth factor receptors and their ligands in development, differentiation, and cancer.

Authors:  A F Wilks
Journal:  Adv Cancer Res       Date:  1993       Impact factor: 6.242

7.  Molecular cloning and chromosomal localisation of the human homologue of a receptor related to tyrosine kinases (RYK).

Authors:  S A Stacker; C M Hovens; A Vitali; M A Pritchard; E Baker; G R Sutherland; A F Wilks
Journal:  Oncogene       Date:  1993-05       Impact factor: 9.867

8.  Confidence limits for estimates of gene linkage based on analysis of recombinant inbred strains.

Authors:  J Silver
Journal:  J Hered       Date:  1985 Nov-Dec       Impact factor: 2.645

9.  The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus.

Authors:  B Chabot; D A Stephenson; V M Chapman; P Besmer; A Bernstein
Journal:  Nature       Date:  1988-09-01       Impact factor: 49.962

Review 10.  Chromosome maps of man and mouse. IV.

Authors:  A G Searle; J Peters; M F Lyon; J G Hall; E P Evans; J H Edwards; V J Buckle
Journal:  Ann Hum Genet       Date:  1989-05       Impact factor: 1.670
  10 in total
  1 in total

1.  Functional analysis of H-Ryk, an atypical member of the receptor tyrosine kinase family.

Authors:  R M Katso; R B Russell; T S Ganesan
Journal:  Mol Cell Biol       Date:  1999-09       Impact factor: 4.272
  1 in total

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