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Literature DB >> 7613027

Localization of genes for two members of the JAK family of protein tyrosine kinases to murine chromosomes 4 and 19.

N M Gough¹, S Rakar, A Harpur, A F Wilks.

Abstract

Genes encoding two members of the JAK family of protein tyrosine kinases, Jak-1 and Jak-2, have been mapped to mouse Chromosomes (Chrs) 4 and 19 respectively. These placements are consistent with the previously described location of human JAK1 and JAK2, which lie in regions of synteny on human Chrs 1p31-3 (JAK1) and 9p24 (JAK2). The location of Jak-2 in the mouse genome extends the region of homology between mouse Chr 19 and human Chr 9.

Entities: Gene Species

Mesh：

Substances：

Year: 1995 PMID： 7613027 DOI： 10.1007/BF00352409

Source DB: PubMed Journal: Mamm Genome ISSN： 0938-8990 Impact factor: 2.957

9 in total

1. Mapping the adrenal lipid depletion gene of the AKR/J mouse strain.

Authors: B A Taylor; H Meier
Journal: Genet Res Date: 1975-12 Impact factor: 1.588

2. Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase.

Authors: A F Wilks; A G Harpur; R R Kurban; S J Ralph; G Zürcher; A Ziemiecki
Journal: Mol Cell Biol Date: 1991-04 Impact factor: 4.272

1 in total

1. Jak3 maps to chromosome 8.

Authors: D H Kono; D G Owens; A R Wechsler
Journal: Mamm Genome Date: 1996-06 Impact factor: 2.957

1 in total

Localization of genes for two members of the JAK family of protein tyrosine kinases to murine chromosomes 4 and 19.

1. Mapping the adrenal lipid depletion gene of the AKR/J mouse strain.

2. Two novel protein-tyrosine kinases, each with a second phosphotransferase-related catalytic domain, define a new class of protein kinase.

3. Two members of the JAK family of protein tyrosine kinases map to chromosomes 1p31.3 and 9p24.

Review 4. Protein tyrosine kinase growth factor receptors and their ligands in development, differentiation, and cancer.

5. Confidence limits for estimates of gene linkage based on analysis of recombinant inbred strains.

6. Localization of the gene for plasma retinol binding protein to the distal half of mouse chromosome 19.

7. The relaxin gene is located on chromosome 19 in the mouse.

8. Characterization of the endogenous nonecotropic murine leukemia viruses of NZB/B1NJ and SM/J inbred strains.

9. Two human relaxin genes are on chromosome 9.

1. Jak3 maps to chromosome 8.