Literature DB >> 7606163

Overexpression in Escherichia coli of 12 vitamin B12 biosynthetic enzymes.

C A Roessner1, J B Spencer, S Ozaki, C Min, B P Atshaves, P Nayar, N Anousis, N J Stolowich, M T Holderman, A I Scott.   

Abstract

The first 12 enzymes involved in the biosynthesis of vitamin B12 from its five-carbon precursor, aminolevulinic acid, have been overexpressed in recombinant strains of Escherichia coli. The activity of each enzyme has been demonstrated by the biosynthesis of hydrogenobyrinic acid from aminolevulinic acid.

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Year:  1995        PMID: 7606163     DOI: 10.1006/prep.1995.1019

Source DB:  PubMed          Journal:  Protein Expr Purif        ISSN: 1046-5928            Impact factor:   1.650


  9 in total

1.  Conformational stability of adrenodoxin mutant proteins.

Authors:  T V Burova; V Beckert; H Uhlmann; O Ristau; R Bernhardt; W Pfeil
Journal:  Protein Sci       Date:  1996-09       Impact factor: 6.725

2.  Effect of mutations in the transmethylase and dehydrogenase/chelatase domains of sirohaem synthase (CysG) on sirohaem and cobalamin biosynthesis.

Authors:  S C Woodcock; E Raux; F Levillayer; C Thermes; A Rambach; M J Warren
Journal:  Biochem J       Date:  1998-02-15       Impact factor: 3.857

3.  The role of Saccharomyces cerevisiae Met1p and Met8p in sirohaem and cobalamin biosynthesis.

Authors:  E Raux; T McVeigh; S E Peters; T Leustek; M J Warren
Journal:  Biochem J       Date:  1999-03-15       Impact factor: 3.857

4.  Comparative studies on the 5-aminolaevulinic acid dehydratases from Pisum sativum, Escherichia coli and Saccharomyces cerevisiae.

Authors:  N M Senior; K Brocklehurst; J B Cooper; S P Wood; P Erskine; P M Shoolingin-Jordan; P G Thomas; M J Warren
Journal:  Biochem J       Date:  1996-12-01       Impact factor: 3.857

5.  Cobalamin (vitamin B12) biosynthesis: functional characterization of the Bacillus megaterium cbi genes required to convert uroporphyrinogen III into cobyrinic acid a,c-diamide.

Authors:  E Raux; A Lanois; A Rambach; M J Warren; C Thermes
Journal:  Biochem J       Date:  1998-10-01       Impact factor: 3.857

6.  Enzyme alchemy: cell-free synthetic biochemistry for natural products.

Authors:  Simon J Moore
Journal:  Emerg Top Life Sci       Date:  2019-11-11

Review 7.  Microbial production of vitamin B12: a review and future perspectives.

Authors:  Huan Fang; Jie Kang; Dawei Zhang
Journal:  Microb Cell Fact       Date:  2017-01-30       Impact factor: 5.328

Review 8.  Complexity reduction and opportunities in the design, integration and intensification of biocatalytic processes for metabolite synthesis.

Authors:  Roland Wohlgemuth; Jennifer Littlechild
Journal:  Front Bioeng Biotechnol       Date:  2022-07-22

9.  Effects of Escherichia coli on mixotrophic growth of Chlorella minutissima and production of biofuel precursors.

Authors:  Brendan T Higgins; Jean S VanderGheynst
Journal:  PLoS One       Date:  2014-05-07       Impact factor: 3.240

  9 in total

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