Literature DB >> 7605353

Immunolocalization of BMP-6, a novel TGF-beta-related cytokine, in normal and atherosclerotic smooth muscle cells.

H J Schluesener1, R Meyermann.   

Abstract

We have analyzed expression of a novel transforming growth factor type beta (TGF-beta)-related cytokine, bone morphogenetic protein-6 (BMP-6) in normal and atherosclerotic brain arteries. BMP-6 immunoreactivity was detected in smooth muscle cells of normal cerebral blood vessels. It is also expressed by smooth muscle cells of intimal plaques in atherosclerotically changed blood vessels. The BMPs regulate tissue modeling and remodeling and aberrant expression of BMPs might contribute to smooth muscle cell migration, proliferation, tissue reorganization and macrophage attraction, which are known mechanisms of atherosclerotic plaque formation.

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Year:  1995        PMID： 7605353     DOI： 10.1016/0021-9150(94)05438-o

Source DB:  PubMed          Journal:  Atherosclerosis        ISSN： 0021-9150            Impact factor:   5.162


  15 in total

Review 1.  Gene therapy for restenosis.

Authors:  R C Smith; K Walsh
Journal:  Curr Cardiol Rep       Date:  2000-01       Impact factor: 2.931

2.  Inhibition of bone morphogenetic proteins protects against atherosclerosis and vascular calcification.

Authors:  Yucheng Yao; Brian J Bennett; Xuping Wang; Michael E Rosenfeld; Cecilia Giachelli; Aldons J Lusis; Kristina I Boström
Journal:  Circ Res       Date:  2010-06-24       Impact factor: 17.367

3.  Cistanches Herba aqueous extract affecting serum BGP and TRAP and bone marrow Smad1 mRNA, Smad5 mRNA, TGF-β1 mRNA and TIEG1 mRNA expression levels in osteoporosis disease.

Authors:  Hai-Dong Liang; Fang Yu; Zhi-Hong Tong; Hong-Quan Zhang; Wu Liang
Journal:  Mol Biol Rep       Date:  2012-12-12       Impact factor: 2.316

Review 4.  The regulation of valvular and vascular sclerosis by osteogenic morphogens.

Authors:  Kristina I Boström; Nalini M Rajamannan; Dwight A Towler
Journal:  Circ Res       Date:  2011-08-19       Impact factor: 17.367

5.  Bone morphogenetic protein-induced MSX1 and MSX2 inhibit myocardin-dependent smooth muscle gene transcription.

Authors:  Ken'ichiro Hayashi; Seiji Nakamura; Wataru Nishida; Kenji Sobue
Journal:  Mol Cell Biol       Date:  2006-10-09       Impact factor: 4.272

6.  Inhibition of rat vascular smooth muscle proliferation in vitro and in vivo by bone morphogenetic protein-2.

Authors:  T Nakaoka; K Gonda; T Ogita; Y Otawara-Hamamoto; F Okabe; Y Kira; K Harii; K Miyazono; Y Takuwa; T Fujita
Journal:  J Clin Invest       Date:  1997-12-01       Impact factor: 14.808

7.  Anti-inflammatory effect of amlodipine plus atorvastatin treatment on carotid atherosclerosis in zucker metabolic syndrome rats.

Authors:  Xuemei Zhang; Fengfeng Tian; Hiromi Kawai; Tomoko Kurata; Shoko Deguchi; Kentaro Deguchi; Jingwei Shang; Ning Liu; Wentao Liu; Yoshio Ikeda; Tohru Matsuura; Tatsushi Kamiya; Koji Abe
Journal:  Transl Stroke Res       Date:  2012-07-21       Impact factor: 6.829

8.  Elevated serum bone morphogenetic protein 4 in patients with chronic kidney disease and coronary artery disease.

Authors:  Paul F Stahls; Daniel J Lightell; Stephanie C Moss; Corey K Goldman; T Cooper Woods
Journal:  J Cardiovasc Transl Res       Date:  2012-12-04       Impact factor: 4.132

9.  Endothelial Bmp4 is induced during arterial remodeling: effects on smooth muscle cell migration and proliferation.

Authors:  Matthew A Corriere; Chris M Rogers; Jonathan L Eliason; Jimbob Faulk; Tsutomu Kume; Brigid L M Hogan; Raul J Guzman
Journal:  J Surg Res       Date:  2007-08-16       Impact factor: 2.192

10.  High-density lipoproteins affect endothelial BMP-signaling by modulating expression of the activin-like kinase receptor 1 and 2.

Authors:  Yucheng Yao; Esther S Shao; Medet Jumabay; Ani Shahbazian; Sheng Ji; Kristina I Boström
Journal:  Arterioscler Thromb Vasc Biol       Date:  2008-10-23       Impact factor: 8.311
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