C H Syrop1, A Willhoite, B J Van Voorhis. 1. Department of Obstetrics and Gynecology, University of Iowa College of Medicine, Iowa City 52242-1080, USA.
Abstract
OBJECTIVE: To determine the potential of ovarian volume as a predictor of assisted reproduction outcomes. DESIGN: Retrospective chart review. SETTING: University-based assisted reproduction program. PATIENTS: One hundred eighty-eight women initiating their first cycle of assisted reproduction. INTERVENTIONS: None. MAIN OUTCOME MEASURES: Pretreatment transvaginal ultrasound ovarian measurements were compared with subsequent ovulation induction parameters (peak E2, numbers of oocytes, and embryos) and cycle outcome (cancellation and pregnancy). RESULT: Total ovarian volume and volume of the smallest ovary were significant variables predicting peak E2 and numbers of oocytes and embryos. Total ovarian volume was a predictor of cycle cancellation and volume of the smallest ovary a predictor of clinical pregnancy. Large ovarian volumes are associated with good assisted reproductive technology outcomes whereas small ovarian volumes are associated with poor outcomes. CONCLUSION: Beyond maternal age, total ovarian volume, and volume of the smallest ovary are significant predictors of the success of assisted reproductive techniques.
OBJECTIVE: To determine the potential of ovarian volume as a predictor of assisted reproduction outcomes. DESIGN: Retrospective chart review. SETTING: University-based assisted reproduction program. PATIENTS: One hundred eighty-eight women initiating their first cycle of assisted reproduction. INTERVENTIONS: None. MAIN OUTCOME MEASURES: Pretreatment transvaginal ultrasound ovarian measurements were compared with subsequent ovulation induction parameters (peak E2, numbers of oocytes, and embryos) and cycle outcome (cancellation and pregnancy). RESULT: Total ovarian volume and volume of the smallest ovary were significant variables predicting peak E2 and numbers of oocytes and embryos. Total ovarian volume was a predictor of cycle cancellation and volume of the smallest ovary a predictor of clinical pregnancy. Large ovarian volumes are associated with good assisted reproductive technology outcomes whereas small ovarian volumes are associated with poor outcomes. CONCLUSION: Beyond maternal age, total ovarian volume, and volume of the smallest ovary are significant predictors of the success of assisted reproductive techniques.
Authors: J P Kusanovic; J K Nien; L F Gonçalves; J Espinoza; W Lee; M Balasubramaniam; E Soto; O Erez; R Romero Journal: Ultrasound Obstet Gynecol Date: 2008-02 Impact factor: 7.299
Authors: Francesca E Duncan; Jennifer K Jozefik; Alison M Kim; Jennifer Hirshfeld-Cytron; Teresa K Woodruff Journal: US Obstet Gynecol Date: 2011-01-01