Literature DB >> 758206

Hemoglobin E trait reexamined: a cause of microcytosis and erythrocytosis.

V F Fairbanks, G S Gilchrist, B Brimhall, J A Jereb, E C Goldston.   

Abstract

The current Indochinese resettlement program in the United States has resulted in an increase in the number of persons with hemoglobin E trait. American physicians should be aware of the hematologic expressions of this innocuous condition. The hematologic manifestations of 21 persons with hemoglobin E trait were evaluated. The subjects were of Tai-dam, Vietnamese, Chinese, Laotian, and European origin. These studies showed uniform hematologic manifestations in hemoglobin E trait, characterized by slight microcytosis, by morphologic features resembling those of thalassemia minor, and often by increased erythrocyte count. Hemoglobin instability also was confirmed.

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Year:  1979        PMID： 758206

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  14 in total

1.  A Czechoslovakian teenager with Hb E-beta zero-thalassemia [IVS-I-1 (G----A)] complicated by the presence of an alpha-globin gene triplication.

Authors:  K Indrak; Y J Fei; H W Li; E Baysal; V Brabec; H Fortova; J Cermak; T H Huisman
Journal:  Ann Hematol       Date:  1991-07       Impact factor: 3.673

2.  Should we screen for globin gene mutations in blood samples with mean corpuscular volume (MCV) greater than 80 fL in areas with a high prevalence of thalassaemia?

Authors:  L C Chan; S K Ma; A Y Chan; S Y Ha; J S Waye; Y L Lau; D H Chui
Journal:  J Clin Pathol       Date:  2001-04       Impact factor: 3.411

3.  Inherited haemoglobin variants in a South African population.

Authors:  A R Bird; P Ellis; K Wood; C Mathew; C Karabus
Journal:  J Med Genet       Date:  1987-04       Impact factor: 6.318

4.  Rapid detection of hemoglobin variants by mutagenically separated polymerase chain reaction (MS-PCR).

Authors:  J G Chang; C P Chang; C M Lu; J M Huang; J T Chen; H J Liu
Journal:  Ann Hematol       Date:  1995-08       Impact factor: 3.673

5.  Hemoglobin E in Europeans: further evidence for multiple origins of the beta E-globin gene.

Authors:  H H Kazazian; P G Waber; C D Boehm; J I Lee; S E Antonarakis; V F Fairbanks
Journal:  Am J Hum Genet       Date:  1984-01       Impact factor: 11.025

6.  Evidence for multiple origins of the beta E-globin gene in Southeast Asia.

Authors:  S E Antonarakis; S H Orkin; H H Kazazian; S C Goff; C D Boehm; P G Waber; J P Sexton; H Ostrer; V F Fairbanks; A Chakravarti
Journal:  Proc Natl Acad Sci U S A       Date:  1982-11       Impact factor: 11.205

7.  Hemoglobin E in Indochinese refugees.

Authors:  T M Cunningham
Journal:  West J Med       Date:  1982-09

8.  Molecular analysis of the beta-thalassemia phenotype associated with inheritance of hemoglobin E (alpha 2 beta2(26)Glu leads to Lys).

Authors:  E J Benz; B W Berman; B L Tonkonow; E Coupal; T Coates; L A Boxer; A Altman; J G Adams
Journal:  J Clin Invest       Date:  1981-07       Impact factor: 14.808

9.  Hemoglobin E: a common hemoglobinopathy among children of Southeast Asian origin.

Authors:  E Katsanis; K H Luke; E Hsu; J R Yates
Journal:  CMAJ       Date:  1987-07-01       Impact factor: 8.262

Review 10.  Thalassemic hemoglobinopathies.

Authors:  M H Steinberg; J G Adams
Journal:  Am J Pathol       Date:  1983-12       Impact factor: 4.307
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