Literature DB >> 7581470

Urethral pressure increase on effort originates from within the urethra, and continence from musculovaginal closure.

P E Petros1, U Ulmsten.   

Abstract

The aim of the study was to determine the contribution of intra-abdominal pressure transmission to urinary continence in the female. Five patients with genuine stress incontinence (GSI) were studied. Pressure transmission was measured in equivalent positions inside and outside the urethra and bladder during the Intravaginal Slingplasty procedure, a surgical operation used for treatment of urinary incontinence, and performed under local anaesthesia. A 6 mm diameter channel was created alongside the urethra. Two separate microtransducer catheters appropriately marked for length were inserted, one inside the urethra, and the other inside the described channel. With the vaginal hammock intact, an average of 10 simultaneous pressure measurements were made intraoperatively in response to coughing and straining in equivalent positions inside the urethra, and directly outside. Significantly higher pressure readings were found inside the urethra (P = 0.0025), indicating that an active component within the urethra may have created this pressure rise. After opening out two suburethral vaginal flaps, large quantities of urine were lost on coughing in all patients. Continence was achieved on tightening the suburethral vagina, indicating that an adequately tight vaginal hammock is a critical element in the continence process. The findings of this study question intraabdominal pressure as a mechanism contributing to continence, but support an alternative mechanism, musculovaginal closure of the urethra.

Entities:  

Mesh:

Year:  1995        PMID: 7581470     DOI: 10.1002/nau.1930140406

Source DB:  PubMed          Journal:  Neurourol Urodyn        ISSN: 0733-2467            Impact factor:   2.696


  20 in total

1.  Transvaginal mesh technique for pelvic organ prolapse repair: mesh exposure management and risk factors.

Authors:  Pierre Collinet; Franck Belot; Philippe Debodinance; Edouard Ha Duc; Jean-Philippe Lucot; Michel Cosson
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2005-10-15

Review 2.  [The development of concepts of female (in)continence. Pathophysiology, diagnostics and surgical therapy].

Authors:  B Liedl; I Schorsch; C Stief
Journal:  Urologe A       Date:  2005-07       Impact factor: 0.639

3.  Urethral pressure response patterns induced by squeeze in continent and incontinent women.

Authors:  Pia M Teleman; Anders Mattiasson
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  2007-01-05

4.  Pathophysiology of stress urinary incontinence.

Authors:  Edward J McGuire
Journal:  Rev Urol       Date:  2004

5.  Effect of abdominal and pelvic floor tasks on muscle activity, abdominal pressure and bladder neck.

Authors:  Baerbel Junginger; Kaven Baessler; Ruth Sapsford; Paul W Hodges
Journal:  Int Urogynecol J       Date:  2010-01       Impact factor: 2.894

6.  Abdominal strength in voiding cystometry: a risk factor for recurrent urinary tract infections in women.

Authors:  Jesus Salinas; Miguel Virseda; Santiago Méndez; Pablo Menéndez; Manuel Esteban; Jesus Moreno
Journal:  Int Urogynecol J       Date:  2015-05-23       Impact factor: 2.894

7.  Role of the pelvic floor in bladder neck opening and closure II: vagina.

Authors:  P E Papa Petros; U Ulmsten
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  1997

8.  Role of the pelvic floor in bladder neck opening and closure I: muscle forces.

Authors:  P E Petros; U Ulmsten
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  1997

9.  Urethral closure is by a reflex musculoelastic mechanism not pressure transmission.

Authors:  Peter Emanuel Petros
Journal:  Int Urogynecol J       Date:  2020-07-23       Impact factor: 2.894

10.  A multicenter study of tension-free vaginal tape (TVT) for surgical treatment of stress urinary incontinence.

Authors:  U Ulmsten; C Falconer; P Johnson; M Jomaa; L Lannér; C G Nilsson; I Olsson
Journal:  Int Urogynecol J Pelvic Floor Dysfunct       Date:  1998
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