| Literature DB >> 7577065 |
M J Silverstein1, A Barth, D N Poller, E D Gierson, W J Colburn, J R Waisman, P Gamagami.
Abstract
The 10-year results of 300 patients with ductal carcinoma in situ (DCIS) without microinvasion are reported; 167 treated with mastectomy and 133 treated with excision and radiation therapy. There was a significant difference in disease-free survival at 10 years, in favour of those treated with mastectomy, 98% versus 81% (P = 0.0004). Multivariate analysis confirmed nuclear grade as the only significant predictor of local recurrence (P = 0.02) or invasive local recurrence (P = 0.03) in patients with DCIS treated with excision and radiation therapy. There was no difference in breast cancer-specific survival or overall survival between the two treatment groups.Entities:
Mesh:
Year: 1995 PMID: 7577065 DOI: 10.1016/0959-8049(95)00283-o
Source DB: PubMed Journal: Eur J Cancer ISSN: 0959-8049 Impact factor: 9.162