Literature DB >> 7573919

The use of "quality-adjusted life years" (QALYs) to evaluate treatment in intensive care.

R K Kerridge1, P P Glasziou, K M Hillman.   

Abstract

This study examines the feasibility of using Quality-Adjusted Life Years (QALYs) to assess patient outcome and the economic justification of treatment in an Intensive Care Unit (ICU). 248 patients were followed for three years after admission. Survival and quality of life for each patient was evaluated. Outcome for each patient was quantified in discounted Quality-Adjusted Life Years (dQALYs). The economic justification of treatment was evaluated by comparing the total and marginal cost per dQALY for this patient group with the published cost per QALY for other medical interventions. 150 patients were alive after three years. Quality of life for most longterm survivors was good. Patient outcome (QALYs) was greatest for asthma and trauma patients, and least for cardiogenic pulmonary oedema. The tentative estimated cost-effectiveness of treatment varied from AUD $297 per QALY for asthma to AUD $2323 per QALY for patients with pulmonary oedema. This compares favourably with many preventative and non-acute medical treatments. Although the methodology is developmental, the measurement of patient outcome using QALYs appears to be feasible in a general hospital ICU.

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Year:  1995        PMID: 7573919     DOI: 10.1177/0310057X9502300309

Source DB:  PubMed          Journal:  Anaesth Intensive Care        ISSN: 0310-057X            Impact factor:   1.669


  9 in total

Review 1.  The limited incorporation of economic analyses in clinical practice guidelines.

Authors:  Joel F Wallace; Scott R Weingarten; Chiun-Fang Chiou; James M Henning; Andriana A Hohlbauch; Margaret S Richards; Nicole S Herzog; Lior S Lewensztain; Joshua J Ofman
Journal:  J Gen Intern Med       Date:  2002-03       Impact factor: 5.128

Review 2.  The use of QALY and non-QALY measures of health-related quality of life. Assessing the state of the art.

Authors:  M Deverill; J Brazier; C Green; A Booth
Journal:  Pharmacoeconomics       Date:  1998-04       Impact factor: 4.981

3.  Performance of two measures of general health-related quality of life, the EQ-5D and the RAND-36 among critically ill patients.

Authors:  Anne Kaarlola; Ville Pettilä; Pertti Kekki
Journal:  Intensive Care Med       Date:  2004-11-03       Impact factor: 17.440

Review 4.  Long-term survival from intensive care: a review.

Authors:  Teresa A Williams; Geoffrey J Dobb; Judith C Finn; Steve A R Webb
Journal:  Intensive Care Med       Date:  2005-08-24       Impact factor: 17.440

5.  Prophylactic anticoagulation to prevent venous thromboembolism in traumatic intracranial hemorrhage: a decision analysis.

Authors:  Damon C Scales; Jay Riva-Cambrin; Dave Wells; Valerie Athaide; John T Granton; Allan S Detsky
Journal:  Crit Care       Date:  2010-04-20       Impact factor: 9.097

6.  Implications of ICU triage decisions on patient mortality: a cost-effectiveness analysis.

Authors:  David L Edbrooke; Cosetta Minelli; Gary H Mills; Gaetano Iapichino; Angelo Pezzi; Davide Corbella; Philip Jacobs; Anne Lippert; Joergen Wiis; Antonio Pesenti; Nicolo Patroniti; Romain Pirracchio; Didier Payen; Gabriel Gurman; Jan Bakker; Jozef Kesecioglu; Chris Hargreaves; Simon L Cohen; Mario Baras; Antonio Artigas; Charles L Sprung
Journal:  Crit Care       Date:  2011-02-09       Impact factor: 9.097

7.  Cost of intensive care in a Norwegian University hospital 1997-1999.

Authors:  Hans Flaatten; Reidar Kvåle
Journal:  Crit Care       Date:  2002-12-18       Impact factor: 9.097

8.  The role of antimicrobial resistance on long-term mortality and quality of life in critically ill patients: a prospective longitudinal 2-year study.

Authors:  Triantafyllia Koukoubani; Demosthenes Makris; Zoe Daniil; Theoniki Paraforou; Vasiliki Tsolaki; Epaminondas Zakynthinos; John Papanikolaou
Journal:  Health Qual Life Outcomes       Date:  2021-03-03       Impact factor: 3.186

9.  A Markov computer simulation model of the economics of neuromuscular blockade in patients with acute respiratory distress syndrome.

Authors:  Alex Macario; John L Chow; Franklin Dexter
Journal:  BMC Med Inform Decis Mak       Date:  2006-03-15       Impact factor: 2.796

  9 in total

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