Anne Kaarlola1, Ville Pettilä, Pertti Kekki. 1. Department of Anaesthesiology and Intensive Care Medicine, Meilahti Hospital, Helsinki University Central Hospital, P.O. Box 340, 00029, Finland. anne.kaarlola@hus.fi
Abstract
OBJECTIVE: To compare two health-related quality of life measures, the preference-based EQ-5D with five questions and the profile-based RAND-36 with 36 questions, in previous critically ill patients. DESIGN: Prospective observational study. SETTING: A ten-bed medical-surgical intensive care unit (ICU) in a tertiary care university hospital. PATIENTS: Of the 2,709 critically ill patients, treated during the years 1995-2000, the 1,099 patients of the 1,443 still alive who returned both mailed measures were included in the study. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: The EQ-5D and the RAND-36 correlated well (P <.001). Ceiling effect was more obvious with the EQ-5D; the values of the RAND-36 varied usually from 0 to 100 in all the three levels of the corresponding EQ-5D question, and the weakest statistically significant differences were between the EQ levels 2 and 3. In particular, the RAND-36 proved to differentiate better the levels of mobility, self-care, and poor outcome. CONCLUSIONS: The EQ-5D and the RAND-36 correlated well, but when more precisely stated information is needed, especially regarding mobility, self-care, or low quality of life levels of previous critically ill patients, the profile-based RAND-36 may discriminate better.
OBJECTIVE: To compare two health-related quality of life measures, the preference-based EQ-5D with five questions and the profile-based RAND-36 with 36 questions, in previous critically illpatients. DESIGN: Prospective observational study. SETTING: A ten-bed medical-surgical intensive care unit (ICU) in a tertiary care university hospital. PATIENTS: Of the 2,709 critically illpatients, treated during the years 1995-2000, the 1,099 patients of the 1,443 still alive who returned both mailed measures were included in the study. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: The EQ-5D and the RAND-36 correlated well (P <.001). Ceiling effect was more obvious with the EQ-5D; the values of the RAND-36 varied usually from 0 to 100 in all the three levels of the corresponding EQ-5D question, and the weakest statistically significant differences were between the EQ levels 2 and 3. In particular, the RAND-36 proved to differentiate better the levels of mobility, self-care, and poor outcome. CONCLUSIONS: The EQ-5D and the RAND-36 correlated well, but when more precisely stated information is needed, especially regarding mobility, self-care, or low quality of life levels of previous critically illpatients, the profile-based RAND-36 may discriminate better.
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