| Literature DB >> 7565906 |
S Simi1, S Morelli, P G Gervasi, G Rainaldi.
Abstract
The clastogenicity of seven anthraquinones was investigated in a V79 Chinese hamster cell line expressing only the reductive pathway enzymes and in three derived cell lines transfected and expressing three rat cytochrome P450 (1A1, 1A2, 2B1). The results have shown that chromosomal aberrations are modulated in similar manner both in parental and transfected V79 cell lines, suggesting that the clastogenicity of these compounds is not mediated by cytochrome P450 dependent monooxygenases.Entities:
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Year: 1995 PMID： 7565906 DOI： 10.1016/0165-7992(95)00034-8
Source DB: PubMed Journal: Mutat Res ISSN： 0027-5107 Impact factor: 2.433