PURPOSE: We evaluated the significance of retroperitoneal lymph nodes detected by computerized tomography (CT) of low stage nonseminomatous germ cell tumor patients. MATERIALS AND METHODS: A blind retrospective review of 143 CTs of low stage nonseminomatous germ cell tumor revealed pathological stage A disease on 89 (62.2%) and pathological stage B disease on 54 (37.8%). A multivariate logistic regression model was used to evaluate the relationships between diameter of the retroperitoneal nodes detected in these CTs and pathological stage. RESULTS: Based on this model, as the diameter of the nodes increased within a 0 to 25 mm. range, the likelihood of pathological stage B disease increased in a continuous fashion. Using a 3 mm. threshold to define nonmetastatic nodes the sensitivity and negative predictive value of CT based staging was 90%. CONCLUSIONS: This measurement scheme improves the accuracy of staging compared to conventional methods.
PURPOSE: We evaluated the significance of retroperitoneal lymph nodes detected by computerized tomography (CT) of low stage nonseminomatous germ cell tumorpatients. MATERIALS AND METHODS: A blind retrospective review of 143 CTs of low stage nonseminomatous germ cell tumor revealed pathological stage A disease on 89 (62.2%) and pathological stage B disease on 54 (37.8%). A multivariate logistic regression model was used to evaluate the relationships between diameter of the retroperitoneal nodes detected in these CTs and pathological stage. RESULTS: Based on this model, as the diameter of the nodes increased within a 0 to 25 mm. range, the likelihood of pathological stage B disease increased in a continuous fashion. Using a 3 mm. threshold to define nonmetastatic nodes the sensitivity and negative predictive value of CT based staging was 90%. CONCLUSIONS: This measurement scheme improves the accuracy of staging compared to conventional methods.
Authors: Salim K Cheriyan; Marilin Nicholson; Ahmet M Aydin; Mounsif Azizi; Charles C Peyton; Wade J Sexton; Scott M Gilbert Journal: Transl Androl Urol Date: 2020-01
Authors: Carlos I Basilio-de-Leo; Christian I Villeda-Sandoval; Carolina Culebro-García; Francisco Rodríguez-Covarrubias; Ricardo A Castillejos-Molina Journal: Can Urol Assoc J Date: 2015 May-Jun Impact factor: 1.862