L R Lee1, L W Hirst, G Readshaw. 1. Department of Surgery, Princess Alexandra Hospital, Woolloongabba, Qld.
Abstract
PURPOSE: To determine the incidence of true unilateral keratoconus on the basis of computerised corneal topography in a group with clinically diagnosed unilateral keratoconus. METHODS: Retrospective review of 295 patients with keratoconus identified 51 patients with a provisional diagnosis of unilateral keratoconus. Thirty-one of these patients were re-examined clinically and 21 patients met the criteria for a clinical diagnosis of unilateral keratoconus. Computerised corneal topographic analysis (Tomey TMS) was then performed. RESULTS: In a group of 21 patients with clinically diagnosed unilateral keratoconus, computerised corneal topographic analysis identified 14 (67%) patients with bilateral keratoconus and seven (33%) patients with true unilateral keratoconus. Contact lens wear had no significant influence (P=0.76) on the topographical diagnosis of keratoconus in the clinically unaffected fellow eye. The estimated incidence of true unilateral keratoconus in the cohort of 295 patients was 4%. CONCLUSIONS: Computerised corneal topography improves sensitivity in detection of true unilateral keratoconus.
PURPOSE: To determine the incidence of true unilateral keratoconus on the basis of computerised corneal topography in a group with clinically diagnosed unilateral keratoconus. METHODS: Retrospective review of 295 patients with keratoconus identified 51 patients with a provisional diagnosis of unilateral keratoconus. Thirty-one of these patients were re-examined clinically and 21 patients met the criteria for a clinical diagnosis of unilateral keratoconus. Computerised corneal topographic analysis (Tomey TMS) was then performed. RESULTS: In a group of 21 patients with clinically diagnosed unilateral keratoconus, computerised corneal topographic analysis identified 14 (67%) patients with bilateral keratoconus and seven (33%) patients with true unilateral keratoconus. Contact lens wear had no significant influence (P=0.76) on the topographical diagnosis of keratoconus in the clinically unaffected fellow eye. The estimated incidence of true unilateral keratoconus in the cohort of 295 patients was 4%. CONCLUSIONS: Computerised corneal topography improves sensitivity in detection of true unilateral keratoconus.
Authors: Lóránt Dienes; Kinga Kránitz; Eva Juhász; Andrea Gyenes; Agnes Takács; Kata Miháltz; Zoltán Z Nagy; Illés Kovács Journal: PLoS One Date: 2014-10-08 Impact factor: 3.240