| Literature DB >> 7546546 |
C Thebtaranonth1, Y Thebtaranonth, S Wanauppathamkul, Y Yuthavong.
Abstract
Activity-guided investigation of Cyperus rotundus tubers led to the isolation of patchoulenone, caryophyllene alpha-oxide, 10,12-peroxycalamenene and 4,7-dimethyl-1-tetralone. The antimalarial activities of these compounds are in the range of EC50 10(-4)-10(-6) M, with the novel endoperoxide sesquiterpene, 10,12-peroxycalamenene, exhibiting the strongest effect at EC50 2.33 x 10(-6) M.Entities:
Mesh:
Substances:
Year: 1995 PMID: 7546546 DOI: 10.1016/0031-9422(95)00260-e
Source DB: PubMed Journal: Phytochemistry ISSN: 0031-9422 Impact factor: 4.072