Literature DB >> 7538620

Design of the EPC-9, a computer-controlled patch-clamp amplifier. 1. Hardware.

F J SIGWorth1.   

Abstract

The EPC-9 patch-clamp amplifier is a digitally controlled analog device for recording currents in membrane patches and in small cells. It has neither front-panel controls nor internal trim adjustments; instead all gain, range-changing, transient cancellation, calibration and other functions are computer controlled. Novel aspects of the circuit design of this instrument are discussed, with special reference to the issues of allowing computer control of all functions.

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Year:  1995        PMID： 7538620

Source DB:  PubMed          Journal:  J Neurosci Methods        ISSN： 0165-0270            Impact factor:   2.390


  10 in total

1.  Neuron-transistor coupling: interpretation of individual extracellular recorded signals.

Authors:  Sven Ingebrandt; Chi-Kong Yeung; Michael Krause; Andreas Offenhäusser
Journal:  Eur Biophys J       Date:  2005-03       Impact factor: 1.733

2.  Cell-transistor coupling: investigation of potassium currents recorded with p- and n-channel FETs.

Authors:  Günter Wrobel; Reinhard Seifert; Sven Ingebrandt; Jörg Enderlein; Holger Ecken; Arnd Baumann; U Benjamin Kaupp; Andreas Offenhäusser
Journal:  Biophys J       Date:  2005-08-12       Impact factor: 4.033

3.  Measurements of membrane patch capacitance using a software-based lock-in system.

Authors:  Andreas Neef; Christian Heinemann; Tobias Moser
Journal:  Pflugers Arch       Date:  2007-01-06       Impact factor: 3.657

4.  Microchip amplifier for in vitro, in vivo, and automated whole cell patch-clamp recording.

Authors:  Reid R Harrison; Ilya Kolb; Suhasa B Kodandaramaiah; Alexander A Chubykin; Aimei Yang; Mark F Bear; Edward S Boyden; Craig R Forest
Journal:  J Neurophysiol       Date:  2014-11-26       Impact factor: 2.714

Review 5.  High bandwidth approaches in nanopore and ion channel recordings - A tutorial review.

Authors:  Andreas J W Hartel; Siddharth Shekar; Peijie Ong; Indra Schroeder; Gerhard Thiel; Kenneth L Shepard
Journal:  Anal Chim Acta       Date:  2019-01-25       Impact factor: 6.558

Review 6.  End-plate acetylcholine receptor: structure, mechanism, pharmacology, and disease.

Authors:  Steven M Sine
Journal:  Physiol Rev       Date:  2012-07       Impact factor: 37.312

7.  Patch-clamp amplifiers on a chip.

Authors:  Pujitha Weerakoon; Eugenio Culurciello; Youshan Yang; Joseph Santos-Sacchi; Peter J Kindlmann; Fred J Sigworth
Journal:  J Neurosci Methods       Date:  2010-07-15       Impact factor: 2.390

8.  Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R.

Authors:  Tal M Dankovich; Rahul Kaushik; Linda H M Olsthoorn; Gabriel Cassinelli Petersen; Philipp Emanuel Giro; Verena Kluever; Paola Agüi-Gonzalez; Katharina Grewe; Guobin Bao; Sabine Beuermann; Hannah Abdul Hadi; Jose Doeren; Simon Klöppner; Benjamin H Cooper; Alexander Dityatev; Silvio O Rizzoli
Journal:  Nat Commun       Date:  2021-12-08       Impact factor: 14.919

9.  Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage-clamp experiments.

Authors:  Chon Lok Lei; Michael Clerx; Dominic G Whittaker; David J Gavaghan; Teun P de Boer; Gary R Mirams
Journal:  Philos Trans A Math Phys Eng Sci       Date:  2020-05-25       Impact factor: 4.226

10.  A miniaturized multi-clamp CMOS amplifier for intracellular neural recording.

Authors:  Siddharth Shekar; Krishna Jayant; M Angeles Rabadan; Raju Tomer; Rafael Yuste; Kenneth L Shepard
Journal:  Nat Electron       Date:  2019-08-15
  10 in total

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