Literature DB >> 7534063

The characterization of two diazepam binding inhibitor (DBI) transcripts in humans.

M Kolmer1, A Rovio, H Alho.   

Abstract

We have investigated the expression of diazepam binding inhibitor (DBI) (also called acyl-CoA-binding protein or endozepine) transcripts in different human tissues and tissue culture cell lines by reverse-transcriptase assisted PCR and RNase protection assay. Two different DBI transcripts capable of encoding polypeptides of 86 and 104 amino acids were detected in all the human tissues and cell lines studied. The transcript coding for the 86 amino acid DBI polypeptide was found to represent the majority of the total DBI transcript pool.

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Year:  1995        PMID： 7534063      PMCID： PMC1136524          DOI： 10.1042/bj3060327

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  34 in total

1.  Putative diazepam binding inhibitor peptide: cDNA clones from rat.

Authors:  I Mocchetti; R Einstein; J Brosius
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

2.  Cloning and expression of cDNA for human diazepam binding inhibitor, a natural ligand of an allosteric regulatory site of the gamma-aminobutyric acid type A receptor.

Authors:  P W Gray; D Glaister; P H Seeburg; A Guidotti; E Costa
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

3.  Complete amino acid sequences of bovine and human endozepines. Homology with rat diazepam binding inhibitor.

Authors:  H Marquardt; G J Todaro; M Shoyab
Journal:  J Biol Chem       Date:  1986-07-25       Impact factor: 5.157

4.  Bovine and human cDNA sequences encoding a putative benzodiazepine receptor ligand.

Authors:  N R Webb; T M Rose; N Malik; H Marquardt; M Shoyab; G J Todaro; D C Lee
Journal:  DNA       Date:  1987-02

5.  Diazepam binding inhibitor gene expression: location in brain and peripheral tissues of rat.

Authors:  H Alho; R T Fremeau; H Tiedge; J Wilcox; P Bovolin; J Brosius; J L Roberts; E Costa
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

6.  Chromosomal localization of the human diazepam binding inhibitor gene.

Authors:  M A DeBernardi; R R Crowe; I Mocchetti; T B Shows; R L Eddy; E Costa
Journal:  Proc Natl Acad Sci U S A       Date:  1988-09       Impact factor: 11.205

7.  Isolation and characterization of porcine diazepam-binding inhibitor, a polypeptide not only of cerebral occurrence but also common in intestinal tissues and with effects on regulation of insulin release.

Authors:  Z W Chen; B Agerberth; K Gell; M Andersson; V Mutt; C G Ostenson; S Efendić; J Barros-Söderling; B Persson; H Jörnvall
Journal:  Eur J Biochem       Date:  1988-06-01

8.  Amino acid sequence of acyl-CoA-binding protein from cow liver.

Authors:  J Mikkelsen; P Højrup; P F Nielsen; P Roepstorff; J Knudsen
Journal:  Biochem J       Date:  1987-08-01       Impact factor: 3.857

9.  Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors.

Authors:  A Guidotti; C M Forchetti; M G Corda; D Konkel; C D Bennett; E Costa
Journal:  Proc Natl Acad Sci U S A       Date:  1983-06       Impact factor: 11.205

10.  Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.

Authors:  J M Chirgwin; A E Przybyla; R J MacDonald; W J Rutter
Journal:  Biochemistry       Date:  1979-11-27       Impact factor: 3.162
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  1 in total

1.  Pathogenesis of peroxisomal deficiency disorders (Zellweger syndrome) may be mediated by misregulation of the GABAergic system via the diazepam binding inhibitor.

Authors:  Rainer Breitling
Journal:  BMC Pediatr       Date:  2004-03-12       Impact factor: 2.125
  1 in total

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