Literature DB >> 7528045

Inter-alpha-trypsin inhibitor polymorphism. An improved phenotyping procedure and two new alleles.

A Harada1, K Umetsu, T Suzuki.   

Abstract

Serum samples treated with chondroitinase ABC and sialidase were investigated for the detection of inter-alpha-trypsin inhibitor (ITI) polymorphism. The improved phenotyping procedure has proved to be the most practical method for ITI phenotyping. The ITI allele frequencies were examined in 2 population samples from Japanese (n = 365) and Thais (n = 150). Three common alleles, ITI*1, ITI*2, and ITI*3 were identified in both populations, but the Thai population showed a higher frequency of ITI*1 and a lower frequency of ITI*3. Two new alleles were found, which were tentatively denoted ITI*Y and ITI*T. The ITI*T allele frequency in Thais was 0.047.

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Year:  1994        PMID： 7528045     DOI： 10.1007/bf01247270

Source DB:  PubMed          Journal:  Int J Legal Med        ISSN： 0937-9827            Impact factor:   2.686


  9 in total

1.  Inter-alpha-trypsin inhibitor polymorphism in African blacks.

Authors:  U Vogt; L Gürtler; H Cleve
Journal:  Electrophoresis       Date:  1992-05       Impact factor: 3.535

2.  A "new" genetic polymorphism of a human serum protein: inter-alpha-trypsin-inhibitor.

Authors:  U Vogt; H Cleve
Journal:  Hum Genet       Date:  1990-01       Impact factor: 4.132

3.  Inter-alpha-trypsin inhibitor (ITI): a useful genetic system in paternity testing. Evidence for polymorphic occurrence of ITI*3 and existence of a new allele, ITI*4.

Authors:  I Yuasa; K Suenaga; Y Saneshige; N Tamaki; K Ito; K Okada
Journal:  Int J Legal Med       Date:  1991       Impact factor: 2.686

4.  The ITI system in South Koreans and Iranians analysed by an improved classification procedure. Distribution of alleles and description of "new" phenotypes.

Authors:  U Vogt; H Cleve; D D Farhud; H W Goedde
Journal:  Hum Genet       Date:  1991-10       Impact factor: 4.132

5.  A study of the genetic polymorphism of human inter-alpha-trypsin-inhibitor (ITI) in the Han population, Chengdu, China.

Authors:  Y Hou; Q Gou; M Wu
Journal:  Hum Genet       Date:  1993-02       Impact factor: 4.132

6.  Two out of the three kinds of subunits of inter-alpha-trypsin inhibitor are structurally related.

Authors:  W Gebhard; T Schreitmüller; K Hochstrasser; E Wachter
Journal:  Eur J Biochem       Date:  1989-05-15

7.  Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan.

Authors:  J J Enghild; I B Thøgersen; S V Pizzo; G Salvesen
Journal:  J Biol Chem       Date:  1989-09-25       Impact factor: 5.157

8.  Human plasma inter-alpha-trypsin inhibitor is encoded by four genes on three chromosomes.

Authors:  M Diarra-Mehrpour; J Bourguignon; R Sesboüé; M G Matteï; E Passage; J P Salier; J P Martin
Journal:  Eur J Biochem       Date:  1989-01-15

9.  Carbohydrate as covalent crosslink in human inter-alpha-trypsin inhibitor: a novel plasma protein structure.

Authors:  T E Jessen; K L Faarvang; M Ploug
Journal:  FEBS Lett       Date:  1988-03-28       Impact factor: 4.124
  9 in total
  1 in total

1.  Genetic polymorphism of the H1 subunit of inter-alpha-trypsin inhibitor.

Authors:  A Harada; K Umetsu; T Suzuki
Journal:  Int J Legal Med       Date:  1995       Impact factor: 2.686
  1 in total

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