Literature DB >> 2450785

Carbohydrate as covalent crosslink in human inter-alpha-trypsin inhibitor: a novel plasma protein structure.

T E Jessen1, K L Faarvang, M Ploug.   

Abstract

The primary structure of inter-alpha-trypsin inhibitor is partially elucidated, but controversy about the construction of the polypeptide backbone still exists. We present evidence suggesting that inter-alpha-trypsin inhibitor represents a novel plasma protein structure with two separate polypeptide chains covalently crosslinked only by carbohydrate (chondroitin sulphate).

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Year:  1988        PMID: 2450785     DOI: 10.1016/0014-5793(88)80670-7

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  17 in total

1.  Positive Mode LC-MS/MS Analysis of Chondroitin Sulfate Modified Glycopeptides Derived from Light and Heavy Chains of The Human Inter-α-Trypsin Inhibitor Complex.

Authors:  Alejandro Gomez Toledo; Jonas Nilsson; Fredrik Noborn; Carina Sihlbom; Göran Larson
Journal:  Mol Cell Proteomics       Date:  2015-09-25       Impact factor: 5.911

2.  A "new" genetic polymorphism of a human serum protein: inter-alpha-trypsin-inhibitor.

Authors:  U Vogt; H Cleve
Journal:  Hum Genet       Date:  1990-01       Impact factor: 4.132

Review 3.  A physiological function of serum proteoglycan bikunin: the chondroitin sulfate moiety plays a central role.

Authors:  Lisheng Zhuo; Antonietta Salustri; Koji Kimata
Journal:  Glycoconj J       Date:  2002 May-Jun       Impact factor: 2.916

4.  Post-translational processing of the inter-alpha-trypsin inhibitor in the human hepatoma HepG2 cell line.

Authors:  A Héron; J Bourguignon; A Callé; H Borghi; R Sesboüé; M Diarra-Mehrpour; J P Martin
Journal:  Biochem J       Date:  1994-09-01       Impact factor: 3.857

5.  Inter-alpha-trypsin inhibitor polymorphism. An improved phenotyping procedure and two new alleles.

Authors:  A Harada; K Umetsu; T Suzuki
Journal:  Int J Legal Med       Date:  1994       Impact factor: 2.686

Review 6.  The inter-alpha-inhibitor family: from structure to regulation.

Authors:  J P Salier; P Rouet; G Raguenez; M Daveau
Journal:  Biochem J       Date:  1996-04-01       Impact factor: 3.857

7.  Inter-α inhibitor proteins maintain neutrophils in a resting state by regulating shape and reducing ROS production.

Authors:  Soe Soe Htwe; Hidenori Wake; Keyue Liu; Kiyoshi Teshigawara; Barbara S Stonestreet; Yow-Pin Lim; Masahiro Nishibori
Journal:  Blood Adv       Date:  2018-08-14

8.  Isolation and characterization of proteoglycans from human follicular fluid.

Authors:  G V Eriksen; I Carlstedt; M Mörgelin; N Uldbjerg; A Malmström
Journal:  Biochem J       Date:  1999-06-15       Impact factor: 3.857

9.  Genetic polymorphism of the H1 subunit of inter-alpha-trypsin inhibitor.

Authors:  A Harada; K Umetsu; T Suzuki
Journal:  Int J Legal Med       Date:  1995       Impact factor: 2.686

10.  Human inter-alpha-inhibitor family in inflammation: simultaneous synthesis of positive and negative acute-phase proteins.

Authors:  M Daveau; P Rouet; M Scotte; L Faye; M Hiron; J P Lebreton; J P Salier
Journal:  Biochem J       Date:  1993-06-01       Impact factor: 3.857

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