Literature DB >> 7521064

Vaccine technologies: view to the future.

N R Rabinovich1, P McInnes, D L Klein, B F Hall.   

Abstract

The development of vaccines to prevent infectious diseases has been one of the most important contributions of biomedical science. Recent advances in the basic sciences are now fueling the development of a new generation of vaccines that will be based on rational design approaches. Two factors are making this possible: an improved understanding of the microbial factors required for virulence and the nature of the immune response to infection. The status of new vaccine technologies is summarized here.

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Year:  1994        PMID: 7521064     DOI: 10.1126/science.7521064

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  17 in total

1.  Lipid nanocapsule as vaccine carriers for his-tagged proteins: evaluation of antigen-specific immune responses to HIV I His-Gag p41 and systemic inflammatory responses.

Authors:  Saurabh Wadhwa; Anekant Jain; Jerold G Woodward; Russell J Mumper
Journal:  Eur J Pharm Biopharm       Date:  2011-10-31       Impact factor: 5.571

2.  Injectable polymer microspheres enhance immunogenicity of a contraceptive peptide vaccine.

Authors:  Chengji Cui; Vernon C Stevens; Steven P Schwendeman
Journal:  Vaccine       Date:  2006-08-17       Impact factor: 3.641

3.  Minimal epitopes expressed in a recombinant polyepitope protein are processed and presented to CD8+ cytotoxic T cells: implications for vaccine design.

Authors:  S A Thomson; R Khanna; J Gardner; S R Burrows; B Coupar; D J Moss; A Suhrbier
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-20       Impact factor: 11.205

4.  Immunisation policies--successes, failures and the future.

Authors:  E Miller
Journal:  J Clin Pathol       Date:  1996-08       Impact factor: 3.411

Review 5.  Drug delivery issues in vaccine development.

Authors:  M F Powell
Journal:  Pharm Res       Date:  1996-12       Impact factor: 4.200

6.  Generation of antiserum to specific epitopes.

Authors:  D C Marchion; D S Manning; W M Shafer; R C Judd
Journal:  Mol Biotechnol       Date:  1996-12       Impact factor: 2.695

Review 7.  [Mumps vaccines: virological basis].

Authors:  A Ströhle; D Germann
Journal:  Soz Praventivmed       Date:  1995

8.  Immunization with chaperone-peptide complex induces low-avidity cytotoxic T lymphocytes providing transient protection against herpes simplex virus infection.

Authors:  Udayasankar Kumaraguru; Malgorzata Gierynska; Shanna Norman; Barry D Bruce; Barry T Rouse
Journal:  J Virol       Date:  2002-01       Impact factor: 5.103

9.  Identification of surface-exposed B-cell epitopes on high molecular-weight adhesion proteins of nontypeable Haemophilus influenzae.

Authors:  S J Barenkam; J W St Geme
Journal:  Infect Immun       Date:  1996-08       Impact factor: 3.441

10.  Stimulation of protective CD8+ T lymphocytes by vaccination with nonliving bacteria.

Authors:  G Szalay; C H Ladel; S H Kaufmann
Journal:  Proc Natl Acad Sci U S A       Date:  1995-12-19       Impact factor: 11.205

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