| Literature DB >> 7515805 |
M Tacker1, W Fontana, P F Stadler, P Schuster.
Abstract
We present and study the behavior of a simple kinetic model for the melting of RNA secondary structures, given that those structures are known. The model is then used as a map that assigns structure dependent overall rate constants of melting (or refolding) to a sequence. This induces a "landscape" of reaction rates, or activation energies, over the space of sequences with fixed length. We study the distribution and the correlation structure of these activation energies.Mesh:
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Year: 1994 PMID: 7515805 DOI: 10.1007/bf00192203
Source DB: PubMed Journal: Eur Biophys J ISSN: 0175-7571 Impact factor: 1.733