Literature DB >> 75057

Differential sensitivities of five rat hepatoma cell lines to anticancer drugs.

S C Barranco, B R Haenelt, E L Gee.   

Abstract

Five permanent tumor cell lines derived originally from either a solid or an ascites biopsy of rat hepatoma exhibited differential sensitivities to bleomycin, Adriamycin, 1-beta-D-arabinofuranosylcytosine, hydroxyurea, 1-trans-(2)-chloroethyl)-3-(4-methoylcyclohexyl)-1-nitrosourea, and 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. The cells were least sensitive to hydroxyurea and 1-beta-D-arabinofurano-sylcytosine, with some cell lines being almost totally resistant to these drugs. However, from 25- to 700-fold differences in survival were obtained between cell lines treated with either bleomycin or Adriamycin.

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Year:  1978        PMID： 75057

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  10 in total

1.  In vitro cellular characteristics and survival responses of human astrocytoma clones to chloroethyl-nitrosoureas and dianhydrogalactitol.

Authors:  N H Rubin; C Casartelli; B G Macik; W R Boerwinkle; S C Barranco
Journal:  Invest New Drugs       Date:  1983       Impact factor: 3.850

2.  Phenotypic drift and heterogeneity in response of metastatic mammary adenocarcinoma cell clones to adriamycin, 5-fluoro-2'-deoxyuridine and methotrexate treatment in vitro.

Authors:  D R Welch; G L Nicolson
Journal:  Clin Exp Metastasis       Date:  1983 Oct-Dec       Impact factor: 5.150

3.  Primary and metastatic liver lesions of clinical colorectal cancer differ in chemosensitivity.

Authors:  Y Maehara; Y Sakaguchi; Y Emi; T Kusumoto; S Kohnoe; M Mori; K Sugimachi
Journal:  Int J Colorectal Dis       Date:  1990-05       Impact factor: 2.571

4.  Heterogeneous responses of an in vitro model of human stomach cancer to anticancer drugs.

Authors:  S C Barranco; C M Townsend; M A Quraishi; N L Burger; H C Nevill; K H Howell; W R Boerwinkle
Journal:  Invest New Drugs       Date:  1983       Impact factor: 3.850

5.  The selective nature of metastasis.

Authors:  J E Talmadge
Journal:  Cancer Metastasis Rev       Date:  1983       Impact factor: 9.264

6.  Comparison of cytostatic sensitivities of L 1210 cells and human stimulated lymphocytes in three cell proliferation assays.

Authors:  F Ali-Osman; H R Maurer
Journal:  J Cancer Res Clin Oncol       Date:  1980       Impact factor: 4.553

7.  Treatment of human cell lines with 5-azacytidine may result in profound alterations in clonogenicity and growth rate.

Authors:  L Olsson; C Due; M Diamant
Journal:  J Cell Biol       Date:  1985-02       Impact factor: 10.539

8.  Assays of drug sensitivity for cells from human tumours: in vitro and in vivo tests on a xenografted tumour.

Authors:  A E Bateman; M J Peckham; G G Steel
Journal:  Br J Cancer       Date:  1979-07       Impact factor: 7.640

9.  Colony growth and clonogenic cell survival in human melanoma xenografts treated with chemotherapy.

Authors:  P J Selby; V D Courtenay; T J McElwain; M J Peckham; G G Steel
Journal:  Br J Cancer       Date:  1980-09       Impact factor: 7.640

10.  Integrated multi-omics data analysis identifying novel drug sensitivity-associated molecular targets of hepatocellular carcinoma cells.

Authors:  Gokhan Yildiz
Journal:  Oncol Lett       Date:  2018-05-04       Impact factor: 2.967
  10 in total

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