Literature DB >> 749701

The effect of zinc on alkaline phosphatase activity in rheumatoid synovial tissue.

J J Johnstone, L Bitensky, B Cashman, J Chayen.   

Abstract

To examine the reported beneficial effect of zinc in rheumatoid arthritis, rheumatoid synovial tissue has been maintained in vitro in non-proliferative culture with or without zinc sulphate in the culture medium. Alkaline phosphatase activity was measured by microdensitometry of the cytochemical reaction in cryostat sections; the activity in blood vessels was measured separately from that in the supporting tissue below the synovial surface. Zinc enhanced this activity optimally at concentrations of between 10(-5) and 10(-4) mol/l.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 749701      PMCID： PMC1000294          DOI： 10.1136/ard.37.6.552

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  12 in total

1.  DIAGNOSTIC criteria for rheumatoid arthritis: 1958 revision by a committee of the American Rheumatism Association.

Authors: 
Journal:  Ann Rheum Dis       Date:  1959-03       Impact factor: 19.103

2.  The culture of mature organs in a synthetic medium.

Authors:  O A TROWELL
Journal:  Exp Cell Res       Date:  1959-01       Impact factor: 3.905

3.  The inhibition of alkaline phosphatase by L-p-bromotetramisole.

Authors:  M Borgers; F Thoné
Journal:  Histochemistry       Date:  1975-08-28

4.  The mechanism of hydrolysis of beta-glycerophosphate by kidney alkaline phosphatase.

Authors:  J Ahlers
Journal:  Biochem J       Date:  1975-09       Impact factor: 3.857

5.  Effect of glucocorticoids on the hexose monophosphate pathway in human rheumatoid synovial lining cells in vitro and in vivo.

Authors:  L Bitensky; B Cashman; J J Johnstone; J Chayen
Journal:  Ann Rheum Dis       Date:  1977-10       Impact factor: 19.103

6.  Effect of glucocorticoids on lysosomes in synovial lining cells in human rheumatoid arthritis.

Authors:  L Bitensky; R G Butcher; J J Johnstone; J Chayen
Journal:  Ann Rheum Dis       Date:  1974-01       Impact factor: 19.103

7.  Letter: Zinc, penicillamine, and rheumatoid arthritis.

Authors:  W H Lyle
Journal:  Lancet       Date:  1976-09-25       Impact factor: 79.321

8.  The maintenance of human synovial tissue in vitro.

Authors:  L W Poulter; L Bitensky; B Cashman; J Chayen
Journal:  Virchows Arch B Cell Pathol       Date:  1970

9.  Changes in alkaline phosphatase activity in periosteal cells in healing fractures.

Authors:  R Shedden; J Dunham; L Bitensky; A Catterall; J Chayen
Journal:  Calcif Tissue Res       Date:  1976-11-24

10.  Oral zinc sulphate in rheumatoid arthritis.

Authors:  P A Simkin
Journal:  Lancet       Date:  1976-09-11       Impact factor: 79.321
View more
  3 in total

1.  5' nucleotidase activity in the human synovial lining in rheumatoid arthritis.

Authors:  B Henderson; J J Johnstone; J Chayen
Journal:  Ann Rheum Dis       Date:  1980-06       Impact factor: 19.103

2.  A comparison of therapies which may influence trace metals in rheumatoid arthritis.

Authors:  J S Dixon; H A Bird; K E Surrall; N G Sitton; V Wright
Journal:  Clin Rheumatol       Date:  1984-12       Impact factor: 2.980

3.  Zinc sulphate in rheumatoid arthritis.

Authors:  P C Mattingly; A G Mowat
Journal:  Ann Rheum Dis       Date:  1982-10       Impact factor: 19.103
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.